crackmitacsAll disciplines

Medicine

2 Mitacs Globalink (GRI) research projects for Summer 2027.

1. Granzymes in impaired wound healing

The research project will focus on characterizing the role of granzymes in tissue injury and impaired wound healing pertaining to aging-related, chronic inflammatory conditions (including pressure injuries, diabetic wounds) using in vitro assays, in vivo disease models, and patient samples. Methodologies used may include: transcriptomics, proteomics, histology, immunohistochemistry, immunofluorescence, immunoblotting, protease assays, ELISAs, and cell culture. The student will have the opportunity to co-author research publications should significant findings arise from their contributions.

Research area, student roles & skills

Research area: The overarching theme of my research program is to better understand the mechanisms underlying tissue injury and wound healing in aging-related, chronic inflammatory conditions. Through phenotypic and molecular characterizations using in vitro studies, in vivo models, and patient biospecimens, our goal is to identify therapeutic targets that could be modulated to improve disease severity and clinical symptoms in patients. In particular, our team is interested in a family of serine proteases known as granzymes (granule-secreted enzymes). Over the past 20+ years, our team has discovered a pathogenic role for granzymes in many age-related, chronic inflammatory conditions/diseases in diverse tissues.

Student roles:
The student will be immersed in a wide range of translational research activities and will work with a Postdoctoral Fellow or Senior Graduate Student supervisor. Day to day tasks will include designing studies, running experiments, scientifically documenting methodology and results, analyzing and interpreting findings, discussing data with supervisors, organizing data into presentations, delivering presentations at lab meetings and local research meetings, writing and editing research manuscripts as well as assisting with other lab duties and studies.

Skills required:
We are looking for a highly-motivated, committed student with a passion for biomedical research and discovery. A background related to immunology, molecular biology, biochemistry, biology, physiology and/or physiology is preferred while previous hands-on experience with techniques such as tissue culture, protein/protease work, immunohistochemistry/histology is an asset. This work term is suitable for a senior student who has previous laboratory experience and is comfortable working independently and on a team. The laboratory is a dynamic, fast-paced, collaborative environment. Excellent written and oral communication skills are essential.

2. Toolkit to Care for Neonates during Armed Conflicts

The research project, Toolkit to Care for Neonates during Armed Conflicts, aims to develop a comprehensive, evidence-based toolkit to support healthcare providers caring for newborns in conflict-affected settings. The toolkit will include practical clinical guidelines, emergency neonatal care protocols, low-resource interventions, infection prevention strategies, and training resources tailored for hospitals, mobile clinics, and humanitarian response teams. The project seeks to improve neonatal survival, strengthen healthcare preparedness, and support frontline workers delivering essential newborn care under conditions of instability, displacement, and limited medical infrastructure.

Research area, student roles & skills

Research area: Neonates are vulnerable during armed conflict. My specialized research area focuses on neonatal and maternal health in humanitarian and conflict settings, with particular emphasis on improving survival and continuity of care for vulnerable newborns during armed conflicts and emergencies. My work integrates global health, neonatal care, emergency preparedness, and health systems strengthening to develop practical, evidence-based interventions for resource-constrained and high-risk environments. The research also explores trauma-informed care, infection prevention, essential newborn care, and the adaptation of clinical protocols for displaced populations and disrupted healthcare systems.

Student roles:
Graduate students fluent in English, who have a background in the health field, are creative, innovative, can analyze literature, develop knowledge translation resources, and have excellent computer skills. The student will conduct an in-depth literature review analysis, write a policy brief report and develop a knowledge translation toolkit in different languages.

Skills required:
Graduate students fluent in English, who have a background in the health field (medicine, nursing or public health), are analytical, creative, innovative, can analyze literature, develop innovative knowledge translation resources, are accountable, maintain effective communication with supervisor/project team, and have excellent communication and computer skills.