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Engg-Biomedical

48 Mitacs Globalink (GRI) research projects for Summer 2027.

1. 3D printing in space

This project explores the development of advanced 3D printing technologies for use in space environments. The selected Mitacs student will investigate materials, processes, and design strategies suited for microgravity conditions, with the goal of enabling on-demand manufacturing during space missions. Responsibilities include experimental design, prototyping, and analysis of print performance in simulated space conditions. The project also examines applications such as in-situ resource utilisation, image processing, tool fabrication, and investigation of layer-wise adhesion via drop adhesion measurement. This research contributes to reducing payload dependency and enhancing mission sustainability, while offering the student hands-on experience in aerospace innovation, additive manufacturing, and interdisciplinary problem-solving in a cutting-edge research setting.

Research area, student roles & skills

Research area: My research focuses on interfacial science and how materials behave where two surfaces meet, such as between liquids and solids. I study how these interactions change in reduced gravity environments, like space or the Moon. In low gravity, forces like surface tension become more important than weight, which affects how liquids spread, stick, or form shapes. Understanding this helps improve technologies like 3D printing, coating, and fluid handling in space. My work aims to make these processes more reliable and efficient, supporting future space missions while also offering insights that can improve material design and manufacturing here on Earth.

Student roles:
-image processing
-CAD modelling
-Experimental design and assembly
-Data analysis

Skills required:
The ideal student should have a background in mechanical engineering, materials science, physics, or a related field. Basic knowledge of engineering and mathematics is required. The student should be comfortable with problem-solving, data analysis, and using software tools for modeling or design. Strong communication skills and the ability to work both independently and in a team are important. An interest in space research, innovation, and hands-on experimentation will help the student succeed in this project.

2. A computational investigation into the sex-based load propagation differences of the isolated lower extremities

Lower extremity injuries represent a significant source of morbidity in automotive crash, occupational, and military impact scenarios. Computational human body models (HBMs) are increasingly used to predict injury risk and evaluate protective systems in these contexts; however, the biomechanical response of male and female models under isolated axial lower extremity loading has not been systematically characterized. Critically, male and female lower extremities differ in bone geometry, cross-sectional morphology, joint alignment, and soft tissue distribution. These differences may produce meaningfully distinct load propagation pathways under identical impact conditions and should be investigated as a potential cause for an increased prevalence in female lower extremity injury in automotive collisions. This project will conduct a controlled computational investigation comparing the below-knee axial impact response of the Global Human Body Models Consortium (GHBMC) 50th percentile male (M50) and 50th percentile female (F50) finite element models. Both models are developed from independent subject imaging data, making geometric differences between them representative of true population-level sex-based morphological variation rather than scaling artifacts. The study will apply a standardized plantar surface axial load (5 m/s, ~150 ms duration) to isolated below-knee segments of both models and quantify differences in force transmission, internal load distribution across osseous and soft tissue structures, and regional strain response from the foot through the tibia. Simulations will be conducted in LS-DYNA using explicit finite element analysis. Results will be reported as time-history response corridors with systematic comparison of load propagation pathways between the two models. Findings will directly inform the suitability of existing HBMs for sex-disaggregated injury risk assessment and will identify structural determinants of observed response differences, contributing foundational data to the injury biomechanics community's broader effort to develop biofidelic computational tools representative of diverse occupant populations.

Research area, student roles & skills

Research area: My research program is focused on impact biomechanics, aiming to enhance the safety and survivability of injurious events, in motor vehicle and defence-related applications. This field of study seeks to understand the human body response to high-rate loading, the mechanism for injury or trauma, and methods to mitigate this injury. This involves investigating the effect of applied loading on post-mortem human subjects, or ‘PMHS’, and the effective translation to surrogates; either mechanical, such as Anthropomorphic Test Devices, ‘ATDs’ (‘crash test dummies’), or computational, such as finite element model human body models, HBMs.

Student roles:
Under the supervision of the host professor, the student will take primary responsibility for the execution and analysis of the computational simulation study. The student's role encompasses four main phases of work across the 12-week internship.
In the first phase, the student will familiarize themselves with the GHBMC M50 and F50 model architectures, with particular focus on the below-knee skeletal and soft tissue components. They will conduct a structured review of anatomical and geometric differences between the two models relevant to axial load transmission, documenting key morphological parameters including bone cross-sectional geometry, joint alignment, and tissue mass distribution.
In the second phase, the student will develop and verify the simulation setup in LS-DYNA, including isolation of the below-knee segment, application of boundary conditions replicating a 5 m/s plantar axial impact of approximately 150 ms duration, and definition of output requests for force, stress, and strain across target anatomical structures. Both models will be prepared using consistent methodology to ensure comparability of outputs.
In the third phase, the student will execute simulations, perform quality control checks on model stability and energy balance, and extract time-history response data. They will systematically compare load propagation pathways between the M50 and F50, identifying where and when load distribution diverges between models and characterizing the structural features driving observed differences.
In the final phase, the student will synthesize findings into a technical report suitable for journal submission and prepare a formal presentation of results. The student will work closely with the supervising professor throughout, participating in regular progress meetings and receiving guidance on scientific interpretation, academic writing, and research methodology in injury biomechanics.

Skills required:
The student should have an undergraduate or graduate background in mechanical engineering, biomedical engineering, or a closely related field, with demonstrated coursework or experience in finite element analysis and solid mechanics. Familiarity with LS-DYNA or equivalent explicit FE software is strongly preferred. Experience with computational biomechanics, musculoskeletal modelling, or human body model simulation is an asset. The student should be comfortable working with large-scale FE models, interpreting force-displacement and stress/strain outputs, and communicating technical findings in written and oral form. Programming experience in MATLAB or Python for post-processing is beneficial but not required.

3. A real-time system for triggering muscle stimulation based on EMG measurements

Devices using functional electrical stimulation (FES) have been successful in re-training hand function following spinal cord injury and stroke. However, triggering of FES is still rudimentary: it is triggered by tapping the stimulation device with the other hand or by moving the head. In this context, current stimulation devices would highly benefit from a design feature that triggers FES based on the user's muscle activity. Such biofeedback would allow seamless and effortless triggering of stimulation. It has also been shown to be an effective therapy modality to re-teach function after neural injury. In this project, we aim to develop a prototype for triggering FES based on electromyography (EMG) measurements. Specific aims are to: 1) Identify potential strategies for triggering FES based on EMG measurements, both in terms of hardware requirements and EMG processing algorithms; 2) Develop a real-time, microcontroller-based environment (e.g., Arduino) for EMG-based triggering of FES; and 3) Test and characterize different EMG processing algorithms when triggering FES. Using previous work on real-time EMG processing, the main objectives are to ensure accurate, robust, and real-time delivery of the FES trigger while minimizing costs. This project is expected to benefit the Canadian industry and healthcare system. It will also allow us to train future biomedical engineers in biomedical instrumentation, real-time control, and bio-signal processing.

Research area, student roles & skills

Research area: Dr. Albert Vette is currently a tenured Full Professor in the Department of Mechanical Engineering, University of Alberta, and a Research Scientist at the Glenrose Rehabilitation Hospital, Edmonton, Canada. His work is centered at the interface between musculoskeletal biomechanics, neuromuscular control, and rehabilitation engineering. Particular research interests of Dr. Vette include the dynamics and control of neuromuscular processes; the modeling of physiological systems; sensory-motor integration during human movement and posture; and assistive technology for individuals with neurological disorders.

Student roles:
Guided by the supervisor and a senior graduate student, the undergraduate student will be responsible for:
- exploring different hardware options and EMG processing algorithms for FES triggering (as part of Aim 1);
- prototyping a test-bed for evaluating different EMG processing algorithms and communication protocols (as part of Aim 2); and
- analyzing the experimental data obtained in Aim 3.
As such, the undergraduate student will be exposed to a range of experimental and analytical techniques.

Skills required:
The student should have a background in Mechanical, Computer, Electrical, or Biomedical Engineering - or any related field. Students should have some knowledge in data acquisition, processing and analysis, and be generally interested in the biomechanics research field.

4. AdaptiveVR: Enhancing Gaming and Therapy through Physiological Feedback

This project aims to use physiological data, such as Galvanic Skin Response (GSR) and Heart Rate (HR), to enhance user experiences in virtual reality (VR) games. By monitoring these metrics, the project seeks to quantify cognitive load and engagement, dynamically managing VR content to optimise the user's experience. Key objectives of the project include: Cognitive Load Assessment: The system will track GSR and HR data to measure an individual's stress levels and cognitive load during VR gameplay. This provides real-time insights into how challenging or engaging the game is for the user. Engagement Monitoring: The system will analyze physiological data to gauge the user's level of engagement in the game. This helps to identify moments of immersion or boredom, allowing the system to adjust content accordingly. Adaptive Content Delivery: Based on the user's physiological responses, the system will dynamically modify the content delivered through VR. For instance, if a user's cognitive load is too high, the system might introduce simpler challenges or calming elements, ensuring the person has a balanced and enjoyable experience. Therapeutic Applications: The system's adaptive capabilities can be particularly valuable for therapy games. By monitoring physiological responses, the system can tailor therapy sessions to maximise learning outcomes, offering a gradual progression in difficulty and maintaining user engagement.

Research area, student roles & skills

Research area: At IDEA Lab (see our website at: goidealab.com) at the University of Alberta, we are focused on developing autonomous intelligent systems to deliver personalized health, specially using wearable, artificial intelligence, and robotic systems. Using these technologies, we measure movement and physiological data. With cost-effective robotic systems, we can perform assessment of human function and deliver therapy. Commonly, we combine these with artificial intelligence (e.g., deep learning) and biomedical signal processing.

Student roles:
The student's role in this project includes:
Data Collection: Integrating physiological sensors to collect GSR and HR data from users during VR gameplay. Preprocessing this data to ensure its suitability for analysis.
Data Analysis: Developing algorithms to interpret the physiological data, quantifying cognitive load and engagement. This includes statistical analysis to identify trends and correlations between gameplay content and user responses.
Content Adaptation: Creating mechanisms to dynamically modify VR content based on the user's physiological responses. This involves designing strategies to balance cognitive load and maintain engagement, particularly for therapy games.
Testing: Evaluating the system's performance in various VR scenarios, assessing its ability to enhance user experiences and therapy outcomes.
Reporting: Documenting the project's progress, methodologies, and findings. Preparing technical reports and contributing to potential academic publications, offering insights into the integration of physiological feedback into VR gaming and therapy.

Skills required:
The ideal student for this project should possess:
A background in computer science, biomedical engineering, or a related field, with coursework in physiology and data analysis.
Proficiency in programming languages such as Python and C#/C++ for VR environment development.
Understanding of physiological sensors, including GSR and HR monitoring devices, and how to interpret their data is an ASSET.
Familiarity with VR systems and gaming design principles is an ASSET.

5. Anti-fouling surfaces

Membranes are replacing many conventional thermal or solvent-based separations technologies. In particular, membranes have made sensitive biological separations possible, for example in separating antibodies from cells grown in batch cell cultures, or in separating industrially treated water from wastewater bioreactors. However, surface fouling is a substantial limitation to membrane operation and is the major cost driver in these purification operations. Fouling reduces flux and can damage the membranes, and as such incurs large operating and capital costs. Our research group is pioneering anti-fouling electrically conductive membranes to tackle this problem. We have shown that by applying an electrical potential to the surface of a porous conductive membrane we can prevent the worst forms of fouling, while decreasing the severity of surface biofouling. However, there are many open questions: 1) what materials are best suited in industry to making conductive membranes? 2) what type of applied electrical potential leads to the greatest anti-fouling? 3) why do different electrical potentials have different effects on fouling development? This project will support a PhD student in the following: A) making electrically conductive membranes using conductive nanomaterials, such as carbon nanotubes (CNTs) and reduced graphene oxide (rGO) B) assess the effects of different applied potentials on the adsorption of biological foulants to the membrane surface

Research area, student roles & skills

Research area: Prof. Charles-Francois de Lannoy’s research is transforming the paradigm of purification technologies and environmental remediation using advanced membranes, electrochemical technologies, nanomaterial composites, and nanosorbents. He is one of the first inventors of electrically conductive membranes and he and his research group are pioneers in using electrochemical technologies for separations and purification applications. These applications includes anti-fouling membranes that can be used in bioreactors, wastewater treatment, biopharmaceutical purifications, and many other industrial processes that contain bacterial colonies.

Student roles:
Summer research students will be engaged in:
1) synthesizing suspensions of nanomaterials in aqueous solutions and solvents
2) synthesizing electrically conductive membranes using film casting techniques
3) setting up electrochemical experiments
4) analyzing the surface of membranes based on various foulants

Students will receive training from a PhD student nanomaterial fabrication, membrane development, and electrochemical techniques.

Students will develop presentation skills through group meeting presentations, poster presentations at the end of the term, and a technology pitch competition internal to the department.

Skills required:
Required skills:
- experience working in a wet lab, e.g. handling solvents, pipetting, making solutions and suspensions
- interest in electrochemistry
- a love of material science
- good collaboration
- clear communication

Additional skills that are not necessary:
- experience working with membranes
- experience with proteins and bacteria
- experience with electrochemistry

6. Associations between cortical landmarks and responses to stimulation

Transcranial magnetic stimulation (TMS) of the motor cortex leads to measurable responses in the targetd muscle. The goal of this project is to determine whether there is a relationship between brain anatomy and response to TMS recorded in the muscle. The candidate will develop experience in quantifying cortex to skull measurements and quantify associations with TMS responses. The candidate will have the opportunity to work along graduate students.

Research area, student roles & skills

Research area: Our research focuses on the neuronal substrates involved in the control of human locomotion. Areas of expertise include neuroscience, motor control, computer science and engineering. We use techniques such as movement kinematics, EMG, neuronavigated brain stimulation (TMS) and brain imaging with MRI and PET. We study human locomotion both overground and on a split-belt treadmill.

Student roles:
Analyze brain imaging data and transcranial magnetic stimulation responses.
Collaborate with graduate students to conduct the project.

Skills required:
Programming skills an asset. Interest in human motor control and neuroscience. Interest in teamwork.

7. Augmented reality for cardiology

The goal of this project is to design and develop artificial intelligence to navigate using an augmented reality system using Vision pro with Unity for cardiology.

Research area, student roles & skills

Research area: Our team specializes in image recognition, image classification and machine learning in medical imaging. We work closely with clinical collaborators in the medical imaging department of Sainte-Justine Hospital, one of the largest pediatric center in Canada.

Student roles:
This projet will be organized as follows :
1. Meeting with the clinical team and familiarization with the project (1 week).
2. Software design involving : 1) requirements analysis, design and implementation of a software prototype (6 weeks)
3. Validation and technical writing (2 weeks).

Skills required:
The candidate should have interest in software development, 3D and augmented reality for medical imaging research. The selected candidate will be exposed to cutting edge research in interventional imaging.

8. Biomedical Lab Hack: Designing Low‑Cost Open‑Source Scientific Tools for Biomedical Research

What if you could build real biomedical lab equipment yourself—with a 3D printer, a handful of electronic components, and a good idea? In this project, we invite curious, hands‑on students to join us, where creativity meets science. Instead of buying expensive, black‑box laboratory instruments, you will help design, build, and test low‑cost, open‑source scientific tools for biomedical research. Using 3D printing, Arduino‑style electronics, and clever engineering, you’ll work on practical tools that researchers actually need—tools that are affordable, customizable, and accessible to labs around the world.

Research area, student roles & skills

Research area: Our laboratory specializes in the microfluidic study of blood and complex biological fluids at small scales.We want to explore additional techniques such as droplet generation and acoustofluidics, where acoustic waves are used to manipulate particles and cells within microchannels. The undergraduate intern will contribute to the design and 3D printing of microfluidic components, as well as the integration of Arduino/ESP-based control systems to automate and characterize these platforms. This work sits at the intersection of mechanical fabrication, embedded systems, and experimental fluid physics.

Student roles:
You will:

Explore open‑source scientific hardware and identify opportunities to improve or simplify existing tools
Design mechanical parts using CAD software and fabricate them with 3D printing
Build and program systems using Arduino / ESP‑type microcontrollers, motors, sensors, and actuators
Experiment with motion, vibration, acoustics, optics, or microfluidics
Test your prototypes in realistic lab settings and improve them based on results
Document your work so others can reuse, reproduce, and improve it

This project values curiosity, experimentation, and creativity as much as technical precision.

Skills required:
This project is ideal for undergraduate students who:

Love building, tinkering, or hacking things
Are curious about how lab instruments actually work
Study biomedical engineering, engineering, physics, computer science, or a related field
Enjoy learning by doing (Arduino experience is helpful but not required)
Care about accessible science, global research equity, and open tools

9. Brain–Computer Interfaces and Individual Differences in EEG Decodability

This project asks why some participants are easy to decode from EEG while others remain poor BCI users. Participants will complete controlled visual stimulus and attention tasks while EEG and eye tracking are recorded. We will combine classic EEG responses with trial-wise behavioral markers such as reaction time, accuracy, pupil size, fixation stability, blink rate, and self-reported fatigue. The project will quantify each person’s neural signature: ERP amplitude/latency, alpha peak frequency/power, gamma response strength, spectral signal-to-noise ratio, artifact burden, ocular stability, and trial-to-trial variability. These features will then be linked to decoding performance in single-subject machine-learning pipelines. Rather than only asking “which classifier is best?”, the project asks “what makes a subject decodable?” Interns will compare models across subjects, identify reliable predictors of BCI performance, and test whether eye-tracking and behavioral features can explain or predict individual decoding success. Expected outputs include a ranked subject-decodability index, trial-wise feature tables, baseline BCI classifiers, and a framework for identifying who is likely to produce useful EEG decoding data.

Research area, student roles & skills

Research area: My lab develops EEG-based brain-computer interface and neurotechnology methods that combine brain rhythms, eye tracking, behavioral performance, and machine learning. We are especially interested in individual differences: why some people produce clean, decodable EEG signals while others are harder to classify.

Student roles:
Two interns will work across data collection, feature engineering, and decoding. Intern 1 will help run EEG/eye-tracking experiments, maintain participant/session metadata, score behavioral performance, and extract core ERP, alpha, gamma, and ocular features. Intern 2 will develop the decoding pipeline: train within-subject classifiers, compare cross-validation strategies, quantify subject-level decoding accuracy, and model which neural/behavioral features predict success. Both interns will contribute to quality control, literature review, and reproducible code. Final deliverables should include cleaned pilot data, a subject-level results table, decoding-performance plots, and a short report on candidate predictors of strong versus weak BCI performance.

Skills required:
Students should have Python experience and interest in EEG, brain-computer interfaces, machine learning, statistics, or cognitive neuroscience. Helpful skills include NumPy/pandas, MNE-Python, scikit-learn/PyTorch, signal processing, data visualization, and careful experimental work. Students should be comfortable debugging noisy real-world data.

10. Characterization of unaffected shoulder motion in upper limb prosthesis users

Body-powered prostheses are commonly used by individuals with upper limb loss. Since they are controlled using active body movements via a harness and cable system, much of the function of the affected arm is transferred to the unaffected arm. These movement changes may lead to increased pain and overuse in the unaffected shoulder. In spite of this, it is unknown how movement of the unaffected shoulder compares to that of the affected shoulder and to that in non-disabled individuals. The first objective is to compare the three-dimensional shoulder kinematics between unaffected and affected limbs during two standardized unilateral tasks when performed by individuals with a body-powered prosthesis. The second objective is to compare the three-dimensional shoulder kinematics of the unaffected limb in these prosthesis users to the kinematics of the non-task performing shoulder in non-disabled individuals. The trainee’s first task will be to become familiar with previously collected motion capture data for non-disabled and prosthesis user participants. The trainee’s subsequent tasks will include pre-processing the data, preparing the data for kinematic analysis, and analyzing the data. Three-dimensional shoulder kinematics will be calculated using the previously developed software Gaze and Movement Assessment (GaMA). Range of motion and peak angle measures will be extracted for three-dimensional shoulder kinematics for the unaffected limb and statistically compared to the affected shoulder in prosthesis users as well as to the non-task performing shoulder in non-disabled individuals. We hypothesize that prosthesis users may show compensations in the movement of the sound shoulder when using a body-powered prosthesis. Understanding the extent of movement deviations of the shoulder in the unaffected side may shed light on sources of overuse and be useful for improving the design of prosthetic technologies and their quantitative assessments.

Research area, student roles & skills

Research area: Dr. Albert Vette is currently a tenured Full Professor in the Department of Mechanical Engineering, University of Alberta, and a Research Scientist at the Glenrose Rehabilitation Hospital, Edmonton, Canada. His work is centered at the interface between musculoskeletal biomechanics, neuromuscular control, and rehabilitation engineering. Particular research interests of Dr. Vette include the dynamics and control of neuromuscular processes; the modeling of physiological systems; sensory-motor integration during human movement and posture; and assistive technology for individuals with neurological disorders.

Student roles:
The first task will be to ensure that motion capture markers are labelled properly in both the non-disabled and prosthesis user data sets. Then, the data will be used to calculate three-dimensional joint kinematics for the left and right shoulder using the GaMA software. The trainee will extract and statistically compare relevant kinematic measures, namely range of motion, peak angle, and peak angular velocity. In parallel to this work, the trainee will conduct a literature review and draft a manuscript. The trainee will gain valuable scientific experience within a biomedical research program and apply her/his academic knowledge to a clinically relevant problem. She/he will benefit from a wide range of expertise, learn about clinical challenges and needs as they relate to prosthesis user movement assessment, and develop a professional network that will be beneficial in the future. We plan to publish the work in a clinically relevant journal, which will allow the trainee to gain valuable writing experience and further strengthen her/his resume.

Skills required:
The student should have a background in Mechanical, Computer, Electrical, or Biomedical Engineering - or any related field. Students should have some knowledge in data acquisition, processing and analysis, and be generally interested in the biomechanics research field.

11. Classification of medical diagnoses from clinical neurophysiological recordings

This project aims to develop automated methods for differentiating patient diagnoses using routine clinical electroencephalography (EEG) data. Leveraging established academic-clinical collaborations, this initiative will use an extensive and unique dataset of EEG recordings from four British Columbia hospitals, complete with corresponding clinical reports and ICD-10 diagnostic codes. The goal is to create advanced computational tools to enhance decision-making in EEG assessment. The primary objective is to develop and validate machine learning models, including deep learning architectures, that directly predict medical diagnoses (ICD-10 codes) from EEG recordings. While EEG rhythms are known markers of brain activity and dysfunction, previous predictive studies have often used smaller samples. This project capitalizes on a large, diverse dataset to build robust models for classifying a wide spectrum of clinical conditions based on quantitative EEG features. Your core role will involve working with this clinical EEG database to develop and evaluate diagnostic prediction models. Key tasks include training various machine learning classifiers (SVMs, Random Forests, Neural Networks), and evaluating their performance in distinguishing diagnostic categories. Identifying informative EEG features and interpreting model decisions will be crucial. This research offers a significant opportunity to develop innovative AI tools for neurophysiological analysis and improve neurological diagnostic pathways. This project is part of a larger research initiative uniting leading institutions and hospitals around routine clinical EEG data. This broader effort focuses on applying cutting-edge data science to the rich neurological information (EEG time series, expert reports, diagnoses) generated by partner hospitals, ultimately advancing clinical neurophysiology and healthcare through data-driven insights.

Research area, student roles & skills

Research area: My research program is dedicated to translating insights derived from non-invasive neuroimaging modalities, specifically electroencephalography (EEG), magnetoencephalography (MEG), and magnetic resonance imaging (MRI), into clinically relevant applications for brain disorders. Leveraging my dual affiliation as a scientist at Simon Fraser University and within local public hospitals, I explore how variability and pathological alterations in these brain signals manifest across diverse neurological populations and throughout typical development and ageing processes. A central aim is to elucidate the functional correlates of this neurophysiological variability, with the ultimate goal of developing and validating clinically translatable computational methods that enhance diagnostic accuracy.

Student roles:
The student intern's primary responsibility will be to analyze associations between patients’ age and electroencephalograms (EEGs) from an extensive clinical database. This will involve employing advanced statistical techniques (largely in Python), including predictive analytics and machine learning models, to identify correlations and potential predictive relationships. Key tasks include data preprocessing, feature extraction, model development, and validation of analytical pipelines.
A significant component of this role involves disseminating research outcomes. The intern will be expected to contribute substantially to, and potentially lead, the preparation of a research manuscript suitable for peer-reviewed publication. This will entail articulating the study's rationale, methodology, results, and their broader scientific implications.
Furthermore, the intern will actively collaborate with other students and researchers within the broader research initiative focused on clinical EEG and data science applications. This collaborative engagement is crucial for exchanging knowledge, addressing methodological challenges, and advancing the collective development of AI tools in clinical neurophysiology and healthcare.

Skills required:
The ideal candidate for this internship will possess a strong academic background in a quantitative discipline. This typically includes fields such as Mathematics, Statistics, Computer Science, Physics, Engineering, or a closely related area with a significant analytical component, providing the foundational knowledge necessary for complex data analysis and modeling.
Familiarity with Python is beneficial, as it will be the primary tool for data manipulation, analysis, and algorithm implementation within this project.
Furthermore, the candidate should have an understanding of statistical principles and techniques. Prior experience applying machine learning concepts, even in academic coursework or personal projects, would be advantageous.

12. Code a user interface for a Skinner’s box test

We actually are using different rat behaviour testing box that we have built. They are Arduino based system, written by non-professional. The actual problem is that we have no interface, every detail of a particular experiment is hard coded and need to be uploaded every time. For this project, we want to have a set of menu display into graphic display and keypad to be able to change important values. The actual code is not very robust and does not handle errors very well. Some improvement of the code will be needed. We 3D print most of the parts, so we can integrate new detectors, limits switch, etc.

Research area, student roles & skills

Research area: My laboratory is specialized in: neuroscience, behaviour, immunohistochemistry, rat, brain, reward system, surgeries and electrophysiology. For this project: C: arduino, Python.

Student roles:
To code a graphic interface with menu for 2 or more different behaviour analysis test. Redesing 3D pieces to allow better functioning, less exceptions and bugs.
Make the database more easily accesible.

Skills required:
Bases in programing (Python, Arduino, Raspberry Pi or others), in 3D design and print. PCB desing. Bases in electronics or basic robotics. Interest in Node-Red, SQL.

13. Design and fabrication of hydrogel composite system with superior nutrient biotransport and mechanical properties for cartilage tissue engineering

Lesions found on cartilage surface of synovial joints cannot heal spontaneously after reaching critical size of more than 3 mm diameter. If these lesions are not treated, cartilage will undergo chronic degeneration and progress into a painful and debilitating joint disease, known as osteoarthritis. Tissue engineering provides a promising approach to re-surface osteoarthritic joints. However, there are major challenges related to growing large tissue constructs in the lab, such as a lack of nutrient availability at the centre of the constructs. Cells embedded in the core of the constructs are deprived of necessary nutrients for tissue growth, leading to cell death and tissue necrosis. As a way to overcome this challenge, the so-called ‘nutrient channels’ have been created to facilitate biotransport to the interior of large tissue constructs. However, these channels are millimeter-sized hollow cylinders that extend the full depth of the tissue construct, compromising the mechanical properties of the constructs and preventing immediate implantation for cartilage repair. Melt-electrowriting (MEW) is an advanced three dimensional printing technique that is able to produce fibrous scaffold with fine fibre diameter of <50 µm, which has been shown to significantly improve the mechanical stiffness of hydrogels to a value similar to the native cartilage. If the polymer used for MEW is dissolvable in aqueous solution, such as polyvinyl alcohol, MEW may be used to create hydrogels with nutrient channels of micrometer-sized, minimizing the effect of hollow channels on hydrogel stiffness. The goal of this research is to design and fabricate a multi-material MEW scaffold that can produce micro-channels in the hydrogel for nutrient biotransport and simultaneously enable mechanical reinforcement. The hypothesis is that mechanical reinforcement and micro-channel formation can be achieved separately by using two distinct polymeric groups, and the effects of both can be combined by innovative engineering design.

Research area, student roles & skills

Research area: I have worked with biological tissues like articular cartilage and skeletal muscles and polymeric hydrogels such as agarose, and gelatin. I answer research questions through carefully designed in vitro, in situ and in vivo experiments and theoretical modelling. I am interested in unravelling the structure- composition-function relationships and cell-tissue interactions in soft connective tissues. By establishing foundational understanding of how mechanical forces are transduced to the cells, I hope to apply this knowledge in the field of tissue engineering with the ultimate goal of bio-fabricating a viable and functional tissue substitute for patients who suffer from soft tissue injuries/diseases.

Student roles:
The student will be required to design the architecture of two separate MEW scaffolds for mechanical reinforcement and for micro-channel formation. The student will then combine the two designs for a multi-material scaffold that can be used to enhance the mechanical and nutrient transport properties of a hydrogel system (e.g., agarose, alginate, gelatin methacryloyl). The student will be trained to operate the MEW printer and perform 3D printing to fabricate the designed scaffold. The student will also be responsible for collecting experimental data (e.g., mechanical testing) to validate the designed scaffold in the lab.

Skills required:
We are looking for highly motivated biomedical engineering students who are strong in engineering design and eager to learn state-of-the-art 3D printing techniques and prototype development. The students should be comfortable with using standard engineering design software such as Solidworks and Fusion 360.

14. Detecting tactile human-robot interaction

Physical interactions between robots and humans are typically measured using torque sensors at the robot joints, or a 6-axis force/torque sensor at the wrist of the robot. However, these sensors can be expensive, and not all robots are equipped with them. Additionally, they can only provide the general location of a contact: for example, somewhere on the arm or on the hand. Lacking more precise information, the ability of the robot to evaluate the intention behind the contact and to react appropriately is limited. In this project, we are exploring the use of alternative sensors (e.g., close range cameras, acoustic sensors, force sensors built using additive manufacturing), to identify where a contact occurs on the body of a robot, what kind of contact it is, and how much force is applied.

Research area, student roles & skills

Research area: Research at the Human-Robot Interaction lab of the University of Calgary aims to make human-robot interactions safe, comfortable, and intuitive. We specifically research physical interactions between humans and robots. For instance, by regulating the forces between robots and their environment, we can ensure these powerful machines interact respectfully and reliably with people. We are currently working on increasing a robot's awareness of physical contacts: how can a robot know where it is being touched and with how much force? How can it respond appropriately?

Student roles:
Your task will be to design and conduct experiments using different sensors to detect touch, and to analyze the signals captured by the sensors to characterize how well contacts can be identified using the different sensors. For example, your analysis might include converting signals from the time domain to the frequency domain to distinguish contacts from ambient noise, using triangulation to locate the origin of a sound, or using machine learning to classify contacts.

Skills required:
Prior knowledge of linear algebra, partial derivative equations, programming (Python and/or C++), instrumentation, measurements, signal processing and system analysis will be of great help to complete this project!

15. Development and Characterization of Bioengineered Scaffolds for Regenerative Endodontics

Endodontic treatment of immature teeth presents significant challenges due to the presence of an open apex and thin root walls. Regenerative endodontic procedures have emerged as a promising alternative to induce pulp regeneration and promote continued root development. Advances in tissue engineering research rely on three key elements to achieve true regenerative endodontics: stem cells, scaffolds, and signaling agents. Stem cells can originate from any of the periradicular tissues; however, the human apical papilla and dental pulp are the main source of mesenchymal stem cells, which are considered the primary contributors to endodontic regeneration. Scaffolds provide a temporary synthetic extracellular matrix that facilitates the formation of new tissue. A potent signaling agent is essential to stimulate cell migration, proliferation and differentiation, allowing pulp-like tissue formation while the scaffold is biodegraded. Exploring a bioactive signaling agent with known anti-inflammatory and bioactive effects, stimulating also the migration, proliferation, and osteogenic differentiation of human dental pulp stem cells (hDPSCs) would be essential for successful endodontic regeneration. Therefore, this study proposes the development of a biomaterial capable of delivering this desired signaling agent in a controlled and sustained manner to enhance its therapeutic potential. The biomaterial is expected to exhibit favorable physicochemical characteristics and modulate human dental pulp stem cells behavior. The biological performance of the optimized formulations will be evaluated by assessing cell migration, viability, proliferation, adhesion, and spreading, as well as gene expression of key odontogenic and osteogenic markers, and mineralized matrix deposition under both normal and inflammatory in vitro conditions.

Research area, student roles & skills

Research area: My research focuses on the development of biomaterials based on the principles of tissue engineering, drug delivery, and cell biology, aiming at the regeneration or repair of craniofacial, oral, and dental tissues.

Student roles:
The student will be responsible for completing all necessary training required to carry out the lab-based research project. Under the supervision of a senior lab member and the host supervisor, the student will conduct the proposed project, maintain weekly progress reports, and fulfill all mandatory activities associated with the Mitacs program. At the end of the internship, the student will be expected to submit a final report and contribute to a manuscript based on the work conducted during their internship.

Skills required:
Preference will be given to students with experience in cell culture research, 3D bioprinting technology, and scientific writing, including manuscripts and research reports.

16. Development and Testing of Brain Machine Learning Algorithms and Technologies for Neurological Conditions

We are researching and developing a brain tool that target health management for people with neurological conditions. The tool monitors, advise, and report of the neurological condition locally at a mobile and/or desktop device supported by a cloud infrastructure, which runs the brain data analysis algorithms.

Research area, student roles & skills

Research area: I study Brain systems, which can be studied at different spatial and temporal scales. For the spatial scale, our research is focused on the circuit – regional level scale. For the temporal scale, we focus at the second to minute level scale. We use datasets obtained from EEG (Electroencephalograms) signals of brain computer interface devices. The datasets are analyzed with several computer science techniques (e.g. deep learning) to achieve models that express the brain mechanisms and help us to get insights of their systems for a variety of neurological conditions. See further details at https://www.acs.uwinnipeg.ca/scamorlinga/research/index.htm

Student roles:
Programming, testing and evaluating modules in our solution tool. Some documentation may be required out of the assigned R&D activities.

Skills required:
Python programming, Generative AI tools to produce code, data analysis, data visualization, testing software at application and system level, nice to have some knowledge of hardware and signal processing.

17. Development of a Time-of-Flight Optical Scanning System for Real-Time 2D Depth Reconstruction

This project aims to develop a prototype optical scanning system capable of converting time-domain time-of-flight (DTOF) signals into two-dimensional (2D) depth-resolved maps of light propagation in scattering media. The intern will contribute to both the hardware and computational aspects of the system. On the hardware side, the student will assist in characterizing and optimizing an optical scanning setup that collects DTOF measurements using pulsed near-infrared light and fast photon-detection systems. On the computational side, the student will develop algorithms to reconstruct 2D depth maps from temporal photon-distribution data, leveraging signal-processing and inverse-modeling techniques. The goal is to transform raw DTOF measurements into interpretable spatial representations of optical depth and scattering properties, enabling improved visualization of light transport in tissue-like media. This has direct relevance for biomedical imaging applications such as brain monitoring, tissue diagnostics, and non-invasive optical sensing. The student will gain hands-on experience in optical instrumentation, signal processing, computational imaging, and biomedical optics. The project provides an opportunity to bridge experimental photonics with modern data-driven reconstruction techniques.

Research area, student roles & skills

Research area: We develop advanced optical imaging systems for non-invasive measurement of biological tissue structure and function. Our research focuses on time-resolved diffuse optical techniques, including time-domain time-of-flight (DTOF) sensing, and computational reconstruction methods to convert photon transport measurements into spatial maps of tissue depth and optical properties.

Student roles:
The student will contribute to the development of a time-domain optical scanning system and associated computational reconstruction algorithms. Responsibilities include processing DTOF signals, developing algorithms for depth reconstruction, and validating performance using experimental and simulated datasets.

The student will assist in system calibration, data acquisition, and analysis of photon time-of-flight distributions. They will implement numerical methods to convert temporal photon profiles into spatial depth maps and evaluate reconstruction accuracy under different optical conditions.

The student will work closely with graduate students and postdoctoral researchers in the laboratory and participate in regular research meetings. They will also contribute to visualization of results and preparation of figures for dissemination.

Depending on progress, the student may also assist with experimental system integration, including the alignment of optical components and the optimization of detection parameters.

This project provides interdisciplinary training in optical engineering, computational imaging, and biomedical signal processing.

Skills required:
Background in engineering, physics, computer science, or biomedical engineering. Strong programming skills (Python or MATLAB) required. Familiarity with signal processing, optics, or imaging systems is an asset. Experience with data analysis and mathematical modeling is highly desirable. Interest in optical instrumentation and computational imaging is essential.

18. Development of fused optical fiber components for photonic applications

Various optical manipulations and characterizations will be explored during this internship. Specifically: - fusion of standard (e.g., solid-core) and non-standard optical fibers (e.g., weakly multimode and microstructured), fabrication of single-mode and multimode couplers, and fabrication of photonics/fiber arrays using a state-of-the-art Glass fusion processing setup. A specific training will be provided for using the setup. - Characterization of fiber components using lasers, spectrometers, infrared cameras, and photodiodes. Technical support will be provided to help the intern realize these tasks. - Review of the technical literature related to the internship topic and the required experimental procedures. - Writing detailed technical reports on the laboratory procedures in a scientific style.

Research area, student roles & skills

Research area: Our research group specializes in the design, fabrication and testing of specialty optical fibers and photonic devices for applications in optical communications and optical sensing. The domains of research and applications also extend to quantum technologies and biomedical sensors.

Student roles:
The intern will learn how to use the Glass fusion processing setup and perform a number of experiments (described above). The intern will report to the supervisor by means of in-person meetings (1/week), written weekly reports and technical reports.

Skills required:
- Experience and proficiency with laboratory instruments (e.g. oscilloscope, etc.)
- Basic knowledge of fiber optics
- Good communication skills
- Ability to work inside a team

19. Development of machine-learning-based image segmentation of healthy and diseased cartilage cells

Articular cartilage plays an important role in shock absorption and lubrication for pain-free, smooth joint articulation. Cartilage is a resilient biological material with a unique zone-dependent structure and composition. Maintenance of cartilage integrity is done entirely by the cartilage cells, also known as chondrocytes, which takes up < 4% volumetric fraction of the cartilage in human. Maintaining a healthy number of functional chondrocytes is equivalent to having a strong workforce for tissue maintenance and is thought to be essential for healthy cartilage. During early degeneration of cartilage, such as at the onset of osteoarthritis, chondrocytes are observed to change shape, from ellipsoidal to irregular shape with multiple cytoplasmic projections. The origin and the mechanical consequences of the shape change observed in the chondrocytes are not well understood. In order to understand how tissue degeneration drives the observed cell shape change, it is important to relate the cell morphology to the local stiffness of the tissue. However, the abnormal cells contain overlapping cytoplasmic projections, making it challenging to delineate the outline of single cells by using regular image segmentation tools. Therefore, the primary goal of this project is develop a workflow for three-dimensional (3D) image segmentation of cells from cartilage tissues of different disease states using the state-of-the-art deep learning algorithm “Mask R-CNN”. The secondary goal is to evaluate the efficiency of Mask R-CNN in 3D segmentation of cartilage cells with abnormal shapes. This research project will be conducted in collaboration with the University of Calgary.

Research area, student roles & skills

Research area: I have worked with biological tissues such as articular cartilage and skeletal muscles and polymeric hydrogels such as agarose, and gelatin. I answer my research questions through carefully designed in vitro, in situ and in vivo experiments and theoretical modelling. I am interested in understanding the structure- composition-function relationships and cell-tissue interactions in soft connective tissues. By understanding how mechanical forces are transduced through multi-scales to the cells, I hope to apply this knowledge in the field of tissue engineering with the ultimate goal of bio-fabricating a viable and functional tissue substitute for patients who suffer from soft tissue injuries/diseases.

Student roles:
The student is required to go through the literature of some of the most popular deep-learning image segmentation tools, and will be tasked to set up the Mask R-CNN in the university servers. The students will go through 3D image stacks collected by state-of-the-art multi-photon microscopy, and apply Mask R-CNN to segment 3D cells with normal and abnormal shapes from the cartilage tissues. Morphological analysis of the segmented cells will be performed. Then, a correlation analysis will be perform to investigate the relationship between the cell morphology and the local tissue stiffness.

Skills required:
We are looking for highly motivated student who is strong in machine learning, and biomedical engineering.

20. Distributed Deep Neural Networks

Deep neural networks have shown very promising results in recent years for various image classification and segmentation tasks. However, many patient datasets are typically needed for training these machine learning models to produce highly accurate results. The collection of a suitable number of datasets for model training is often the most limiting factor, especially in a clinical context because of patient privacy concerns as well as unwillingness to share unique patient cases, which is especially relevant for less prevalent diseases. The aim of this proposed research is to develop a novel distributed learning system for training of deep neural networks to overcome the limiting factors of data collection and analysis in a centralized fashion. The main goal of this distributed learning architecture is that the individual patient data does not leave the contributing clinical centers but are only used locally to train the machine learning models, which do not contain any patient data at the individual level anymore. The aim of this research project is to implement and evaluate a traveling model learning approach. The main idea of this approach is that as soon as new data becomes available in a single center, the most recent machine learning model will travel from the central server to the local site where the model parameters are updated using the new available data before traveling back to the central server. The prospective student will develop experience in Python, Tensorflow, and other modern libraries for image processing and machine learning. Additionally, the student may have the opportunity to co-author peer reviewed journal publications.

Research area, student roles & skills

Research area: The primary focus of my research group is to develop, evaluate, and apply new image processing methods, algorithms, and software tools for the analysis of medical images. This includes the image-based extraction of clinically relevant parameters and biomarkers describing the morphology and function of organs. In doing so, we aim to support clinical studies and preclinical research as well as developing and improving computer-aided diagnosis and patient-specific, precision-medicine, prediction models. Additionally, a secondary focus of my research lab is in the area of machine learning, mostly in combination with, but not limited to, medical imaging.

Student roles:
The student will be mainly responsible to develop the advanced convolutional neural networks and image processing methods required for this project. The student will be mentored directly by a senior lab member. Additionally, the student will also be able to take a lead on manuscript writing and preparation for presentation of the results of this project at national and international meetings and scientific journals.

Skills required:
Programming experience (e.g. Java, C++, Matlab, Python) is an essential requisite for this position. Experience or basic understanding of deep neural networks and image or signal processing are helpful but not essential.

21. Early Disease Diagnosis using hyperspectral medical imaging

The project “Early Disease Diagnosis using Hyperspectral Medical Imaging” focuses on developing AI-based methods to detect diseases at an early stage using hyperspectral imaging data. Unlike conventional imaging, hyperspectral imaging captures detailed spectral information from biological tissues, allowing subtle abnormalities and tissue changes to be identified more effectively. The project will explore deep learning techniques to analyze both spectral and spatial information for improved disease classification and diagnosis. Applications may include skin lesion analysis, retinal disease detection, or tissue abnormality assessment. The expected outcome is an accurate and interpretable framework that can support healthcare professionals in making faster and more reliable diagnostic decisions.

Research area, student roles & skills

Research area: My specialized research area lies at the intersection of Artificial Intelligence, Machine Learning, and hyperspectral image analysis, with a growing focus on explainable AI and hybrid quantum–classical learning frameworks. The work centers on developing advanced spectral–spatial models, including convolutional, transformer-based, and graph-driven architectures, to process high-dimensional data for applications such as precision agriculture, medical imaging, and document forensics. A key aspect of this research is designing interpretable and computationally efficient methods that can operate under limited labeled data while maintaining strong generalization.

Student roles:
The student will work as part of the research team on developing AI models for early disease diagnosis using hyperspectral medical imaging data. Their role will include reviewing related research literature, preparing and preprocessing medical imaging datasets, and implementing deep learning models using Python-based tools. The student will also conduct experiments, analyze model performance, and assist in improving the accuracy and interpretability of the proposed methods. In addition, they will participate in regular research meetings, document their progress, and contribute to preparing technical reports or research publications.

Skills required:
The ideal student should have a background in Computer Science, Biomedical Engineering, Data Science, or a related field, with basic knowledge of machine learning and deep learning techniques. Experience with Python programming and familiarity with frameworks such as PyTorch or TensorFlow will be helpful. Some understanding of image processing, medical imaging, or data analysis would be an advantage, although prior experience in hyperspectral imaging is not required. The student should be motivated to learn new concepts, interested in AI applications in healthcare, and comfortable working both independently and within a collaborative research environment.

22. Electromyography Sensor Development and Validation

Surface electromyography (EMG) is used for a variety of applications including prosthetic control. Multichannel EMG or high density EMG (HDEMG) is gaining attention as it increases the amount of information that can be extracted from the surface EMG, the complexity of the setup can be limiting in dynamic conditions. There have been some advances in miniature, wireless and modular HDEMG acquisition systems and the applications of this technology in prosthesis control are promising, particularly in the area of e-textiles. This research project will involve the development and validation of a robust sensor grid using multiple electrodes (HDEMG) that can be placed in an upper limb prosthetic socket. The new technology must be compact, able to withstand the conditions of the prosthesis and record reliable signals. The project will also involve running an experiment to test the prototype against a gold standard HDEMG system. Statistical analysis will need to be completed to compare the two systems for reliability and validity.

Research area, student roles & skills

Research area: My background is in the area of human factors and biomedical engineering. My specific research interests include neuromuscular physiology and rehabilitation of clinical populations as well as occupational physiology. The focus of my research is the use of surface electromyography (sEMG) to monitor muscle activity during movement. sEMG is the measurement of the electrical activity at the skin’s surface, that brings about muscle contraction. The sEMG can be used to examine muscle activation patterns for a variety of applications including improved prosthesis design (artificial limbs). Understanding neuromuscular function in movement efficiency will help develop better models of human movement.

Student roles:
The student will be responsible to work with the research team to investigate various types of sensor grids with the goal of contributing to the development of a novel sensor. This will require extensive research in existing technologies, working with the research team to develop a prototype and testing to determine the validity of such a system. The student will also be involved in completing a research protocol to test the prototype against a gold standard system. This will require the student be involved with experimental setup, participant recruitment, data collection, data analysis and synthesis.

Skills required:
The student should have a background in biomedical engineering or electrical engineering with a strong interest in human movement and biological sensor technology. The student must have both hardware (electronics) and software (programming in Matllab and/or Python) in order to develop the technology. The skills required also include familiarization with data acquisition equipment and hardware, strong mathematical and statistical analysis skills and the ability to critically analyze published research. The student should also have strong communication skills.

23. Fat characterization in bicuspid aortic valves

The project aims to characterize heart fat in cardiac magnetic resonance using 2D and 3D approaches and assess its association with clinical cardiac magnetic resonance imaging. Basic annotations will facilitate the automation of fat in future projects.

Research area, student roles & skills

Research area: My laboratory specializes in cardiac imaging. We develop tools for analysis, automation, and interpretation of cardiac imaging datasets. Our main research theme is 4D flow MRI and our secondary themes are related to cardiac imaging strategies.

Student roles:
The student will focus on standard heart fat annotation ~100 bicuspid aortic valve cases

Skills required:
Data analysis, Matlab, Python are assets. Biomedical or Engineering backgrounds.

24. Integrating Neuroimaging and Eye Tracking to Study Reading Development

This project is focused on a long-term goal of developing objective assessments of reading ability based on eye movements and brain activity. The specific goal of this project is to develop and test a system for gaze-contingent evoked potentials - in other words, time-locking brain activity (measured using EEG) with eye movements during reading. Because brain activity changes on a millisecond-by-millisecond basis, it is essential to know exactly what word someone is looking at when we interpret their brain activity. A common way to do this is to present one word at a time, however this is not how people normally read. The alternative is to synchronize data from an eye tracker with EEG data. The goal of this project is to implement and validate this synchronization. Interns will learn how our EEG and eyetracking systems work, and explore an implement different approaches to synchronizing their data streams. Then, the intern will test and validate this by recording data from human participants while they read. If validation is completed prior to the end of the internship, the next step would be to build this integration into a research protocol for use with children in elementary grades.

Research area, student roles & skills

Research area: The NeuroCognitive Imaging Lab (NCIL) conducts basic and applied cognitive neuroscience research. Much of our research is focused on language and neuroplasticity — how the brain changes with experience. The ultimate goal of our work is to help people live healthier, happier, and more productive lives. Our research primarily uses EEG neuroimaging, combined with data analysis pipelines written largely in Python that include conventional signal processing, machine learning, and AI. Current projects in the lab are focused on brain computer interface development, second language acquisition, reading development in children, and hyperscanning studies of pairs of individuals engaged in conversation.

Student roles:
- Become familiar with necessary background literature for the project
- Become familiar with lab protocols for EEG and eye tracking data collection
- Iteratively implement and test approaches to EEG-eye tracking integration
- Validate EEG data from integrated approach against EEG data from conventional (one word at a time) approach
- Build out software in Python to use the integrated system in a study of reading in children, according to provided specifications
- Validate and test the software from the previous step
- At the end of internship, prepare a written summary of the work and report a summary to the lab group in an oral presentation

Skills required:
Essential skills:
- Python programming
- signal processing
Desired skills:
- experience with EEG data collection
- experience with eye tracking data collection
- experience with EEG data processing
- experience with eye tracking data analysis
- familiarity with the Lab Streaming Layer protocol

25. Investigation into the axial impact response of the THOR-Lx

Anthropomorphic test devices (ATD’s) are an important part of vehicle safety research as they allow for the investigation of new vehicle designs and technologies. They're designed to simulate the physical characteristics of people, in terms of segment masses and articulations. It is important that the response of an ATD accurately reflect the response of people in a loading scenario, such that injury risk is captured. A new ATD has been developed, the THOR (Test device for Human Occupant Restraint) which is being adopted into European and North American regulatory assessments. It offers improved biofidelity (i.e., human-like response) as compared to previously used ATDs, by including more detailed and anatomically correct lower extremities, and a more realistic head and neck. The THOR lower extremity also has more advanced sensors and measurement capabilities, allowing for the collection of more information about injury risk experienced during an impact event. An investigation is warranted of the THOR lower extremity for its axial impact response under varying ankle postures. As PMHS studies have shown that ankle posture influences injury outcome, it is necessary that the THOR lower extremity accurately predict this injury risk during an altered impact event. With advancements in seatbelt and airbag design providing better protection for the head, neck, and torso, lower extremities now represent the most frequent site for serious injuries in frontal motor vehicle collisions. Axial loading represents the most common and consequential loading mechanism to the lower extremity. Ankle posture and its effect on injury risk have not been reflected in current evaluations of ATDs. I would like a researcher to investigate a variety of different ankle postures of this new THOR lower extremity to evaluate how axial load and bending moment (two standard injury metrics) are altered, under loading representative of a frontal collision.

Research area, student roles & skills

Research area: My research program is focused on impact biomechanics, aiming to enhance the safety and survivability of injurious events, in motor vehicle and defence-related applications. This field of study seeks to understand the human body response to high-rate loading, the mechanism for injury or trauma, and methods to mitigate this injury. This involves investigating the effect of applied loading on post-mortem human subjects, or ‘PMHS’, and the effective translation to surrogates; either mechanical, such as Anthropomorphic Test Devices, ‘ATDs’ (‘crash test dummies’), or computational, such as finite element model human body models, HBMs.

Student roles:
The student will conduct experimental biomechanics research evaluating the biofidelity of the THOR lower extremity ATD under axial impact loading. Specifically, the student will investigate how ankle posture influences axial load and bending moment transmission through the lower extremity, using a pneumatic impacting apparatus to deliver applied load. A projectile impacts the plantar surface of the foot, by travelling down an acceleration tube towards the impact chamber via compressed air. Ankle posture will be controlled via an ankle positioner, and the ATD lower extremity suspended overhead within the impact chamber to allow for post-impact motion.
The student will be responsible for designing and executing a repeated-measures impact testing protocol across a range of controlled ankle postures. This includes configuring the THOR lower extremity instrumentation, setting and verifying ankle posture between trials, operating data acquisition systems, and applying appropriate signal processing (filtering, calibration verification) to raw sensor output.
Beyond data collection, the student will analyze results to characterize how posture-dependent changes in load transmission compare across conditions, and will situate their findings within the existing PMHS literature on ankle posture and injury outcome. The ultimate goal is to assess whether the THOR lower extremity captures posture-dependent injury risk in a manner consistent with human cadaveric response data, which is a critical step in validating its use in regulatory impact assessments.
The student will be expected to maintain detailed test documentation, contribute to internal reports, and support preparation of findings for peer-reviewed publication. They will work closely with the supervising faculty member and collaborate with lab personnel and external partners as needed. This is a hands-on, technically demanding role suited to a student with strong laboratory instincts, an interest in injury biomechanics, and a motivation to contribute to research with direct implications for occupant safety in frontal motor vehicle collisions.

Skills required:
Applicants should have (or be pursuing) a degree in mechanical or biomedical engineering, or kinesiology with a biomechanics focus. Preferred skills include experimental research experience (impact or dynamic testing would be a strong asset), instrumentation and data acquisition, and signal processing. Familiarity with ATD operation, lower extremity anatomy, and injury biomechanics is an asset. Strong attention to detail and documentation practices are essential for repeatable test protocols. Experience with MATLAB, Python, or Excel for data analysis is expected. Prior lab-based research experience (e.g., co-op, undergraduate thesis, or equivalent) is also preferred.

26. Machine learning models for classification of cell states from Raman spectra

This project focuses on developing an interpretable machine‑learning model to classify cellular states using Raman spectroscopy data. The student will work with high‑dimensional spectral datasets representing different biological conditions (healthy vs diseased, treated vs untreated) and build a multi‑class classifier using Python‑based ML frameworks. The work involves data preprocessing, feature extraction, model training, and evaluation, with an emphasis on explainability (e.g., feature importance, SHAP values) to identify which spectral regions drive classification decisions. The student will also collaborate with a biology‑focused student to explore how Raman‑derived features relate to transcriptomic signatures, contributing to a multi‑omics understanding of cell states. Transcriptomic data will be processed into a matrix Y, normalized, and reduced using PCA, non‑negative matrix factorization (NMF), or pathway‑activity scoring (GSVA/ssGSEA). The student will then implement multivariate linear regression, partial least squares regression (PLS‑R), and canonical correlation analysis (CCA) to model relationships and to identify shared latent components between Raman spectra and gene‑expression programs. These models will reveal how biochemical vibrational signatures (lipids, proteins, nucleic acids) correspond to gene‑expression pathways (metabolism, stress response, proliferation). The student will generate correlation matrices, heatmaps, and network graphs that map Raman‑important peaks to transcriptomic pathways, producing a biologically interpretable multi‑omics explanation of cell‑state changes.

Research area, student roles & skills

Research area: Our lab focuses on understanding immune responses in cancer and discovering biomarkers for early disease detection. Our interdisciplinary research integrates in vitro diagnostics, spectroscopy, and machine learning to investigate the metabolic reprogramming of immune cells within the tumor microenvironment, with applications spanning both cancer and oral health. The goal is to bridge the gap between fundamental scientific discoveries and clinical applications, particularly in the area of early disease detection.

Student roles:
The student will be responsible for developing a customized computational model to link high-dimensional Raman spectral data with transcriptomic profiles. This will involve refining data processing pipelines to clean, normalize, and organize complex spectral and transcriptomic datasets. The student will implement and optimize machine learning models capable of capturing both linear and nonlinear relationships between cellular Raman spectra and gene expression profiles, enabling accurate prediction and interpretation of omics information. The student will design novel feature extraction and representation learning approaches that go beyond simplistic one-to-one mappings between Raman wavenumbers and genes, aiming to uncover meaningful latent features that better represent underlying biological information. An important aspect of the work will be to interpret model outputs in the context of existing biological knowledge, linking predictive features to known molecular pathways, regulatory networks, or cellular states, thereby providing mechanistic insights into the cellular processes that are reflected in the Raman spectra.

Skills required:
The project requires a student with a strong foundation in machine learning, linear algebra, and multivariate statistics, including experience with regression, PCA, and matrix factorization. Proficiency in Python (numpy, pandas, scikit‑learn, matplotlib) is essential, along with the ability to work with high‑dimensional datasets and implement interpretable models such as SHAP or feature‑importance methods. Familiarity with bioinformatics concepts like pathway scoring or RNA‑seq preprocessing is helpful but not mandatory, as long as the student is comfortable learning domain‑specific tools.

27. Magnetic Soft Robots for Surgery

Lung cancer accounts for 25% of all cancer deaths and affects more people than prostrate, breast and colon cancer combined. There is also a high incidence rate for poor and racialized communities who are more often exposed to poor air quality. Developing early diagnosis and treatment options for patients is key to mitigating these deaths. However, reaching peripheral locations inside the lungs for biopsies or localized therapy remains a persistent challenge. Navigational bronchoscopy where an endoscope is manually navigated remains the gold standard. Robotic assisted minimally invasive surgery can overcome many of these challenges and has added benefits as it minimizes damage to the target site, speeds up recovery times and results in fewer complications. We propose to develop a robotic capsule under 2mm to reach these inaccessible peripheral locations. This capsule will be magnetically actuated and equipped with a needle and storage compartment that can store a biopsy yield. The capsule will be designed using a CAD program, it will then be 3D printed, assembled with it's magnetic components, tested under a magnetic actuation system in an in vitro lung phantom. The student will get hands-on experience in a robotics lab and work with senior researchers. They will also develop their communication skills by presenting their work through multiple avenues.

Research area, student roles & skills

Research area: The HeART (Healthcare Applications for Robotic Technologies) Lab is focused on the fundamental understanding and development of magnetically actuated small-scale robots for surgical and on-chip applications. This involves investigating the design, fabrication, and control of these robotic devices. HeART Lab director Dr. Onaizah has been involved in the development of the first shape-forming magnetic continuum robots to navigate along tortuous anatomical paths and experimentally demonstrated this in realistic in vitro environments. The HeART works closely with clinicians to solve some of the most challenging problems at the forefront of medical robotics.

Student roles:
As a regular part of the team, the intern will be given a desk in one of the team offices. They will be integrated into a group of around 10 students working directly on medical robotics, under the direct supervision of Dr. Onaizah. In addition to this group, the intern will be a regular member of the HeART Lab, and benefit from its associated research ecosystem (e.g., seminars, interactions with other students, facilities). The intern will progressively take ownership of their project using a ramp-up approach. The first couple of weeks of the internship will be dedicated to understanding the research task ecosystem, and the different paths they can take in this context. Paired to a senior member of the team (PhD or Masters' student), careful analysis, reviews and guidance will be provided during the ramp-up period, so that eventually the intern can become more independent and can take initiative on their project. When reaching this point, an iterative and incremental approach will be used to tackle the research objective of this internship: a research question will be designed with their immediate supervisor, and the associated research will be done to tackle this question (including literature review, design analysis, experiments, coding, empirical analysis, when relevant to the research question). Finally, the obtained results will be presented to the other members during a group meeting, and the next steps and research directions will be discussed collectively

Skills required:
Minimum Requirements:
• Background in one of the following disciplines: Mechanical Engineering, Biomedical Engineering, Electrical Engineering, Robotics, Computer Science, or related disciplines
• A willingness to work effectively with staff, students, and visitors from a wide range of backgrounds.

Experience in one of the following areas would be an asset:
• Robot Operating System (ROS) and its Gazebo simulation package
• Object-oriented programming language (e.g., embedded C, Matlab, Python, C++, Java, or LabVIEW)
• Computer Aided Design software (e.g. Solidworks, AutoCAD)
• Computer Aided Manufacturing (3D printing, laser cutting, CNC milling)
• Magnetic Control or Manipulation
• Microfabrication

28. Mechanical Characterization and Modelling of Soft Tissues with Focus on Aorta and Skin

Stream 1: Multimodal Mechanical Characterization of Soft Tissues A single loading mode is insufficient to capture the complex, three-dimensional mechanical behaviour of soft biological tissues. This stream focuses on characterizing tissue response under multiple loading conditions, combining techniques such as indentation (out-of-plane compression), uniaxial and biaxial tension (in-plane loading), and, where appropriate, shear and torsion. Testing may be conducted under quasi-static and dynamic regimes to capture nonlinear and time-dependent behavior. Mechanical measurements are complemented with microstructural information obtained through imaging and histology, enabling structure-function relationships to be explored across healthy and pathological tissues. Stream 2: Improving Data Analysis and Constitutive Modelling This stream focuses on advancing the analysis and interpretation of experimental data and improving constitutive descriptions of soft tissue behaviour. Given the nonlinear, anisotropic, and viscoelastic nature of biological tissues, the project aims to refine how mechanical responses are quantified across loading ranges, regimes, and modes, and to establish consistent, physically meaningful, and microstructurally-informed constitutive frameworks that are capable of capturing key features related to age, pathology, and injury. Stream 3: Finite Element Simulations of Heterogeneity in Aneurysms and Skin Wounds This stream focuses on computational modelling of spatial heterogeneity in soft tissues, with applications to aortic aneurysms and skin wounds. These tissues exhibit significant regional variations in structure and mechanical properties that influence their mechanical response and potential failure. The project aims to incorporate this often-neglected heterogeneity into finite element models to better represent realistic behavior under physiological or functional loading conditions. Simulations will be used to examine how spatial variations in material properties affect stress and deformation patterns, contributing to improved understanding of disease progression, healing, and tissue integrity.

Research area, student roles & skills

Research area: The research group focuses on the biomechanics of soft tissues through integrated experimental, analytical, and computational approaches. Mechanical characterization is performed using selected combinations of indentation, unconfined compression, uniaxial/biaxial tension, shear, and torsion tests, often complemented by microstructural information through micro-CT, multiphoton imaging, ELISA protein assays, and histology. Research activities also extend to constitutive modelling and advanced analytical, FEA, CFD, and FSI simulations that incorporate realistic material behaviour, geometries, and boundary conditions. Research goals range from improving data analysis and advancing fundamental understanding to developing diagnostic tools and evaluating treatments, with applications to healthy and pathological aortic and skin tissues.

Student roles:
All students will contribute to research dissemination through reports, abstracts, and presentations, and will participate in weekly group meetings and supervision or mentorship sessions.

In Stream 1, students will assist in developing testing protocols, conducting experiments, and analyzing mechanical and imaging data, including statistical interpretation.

In Stream 2, students will process and analyze complex experimental datasets, explore relationships between variables, and contribute to the development and evaluation of constitutive models.

In Stream 3, students will support the development of computational models, implement simulations, and analyze outputs to assess the effects of material heterogeneity on tissue mechanics.

Skills required:
All students are expected to participate in EDIA training and to demonstrate strong communication and teamwork skills. A solid foundation in mechanics (stress, strain, basic viscoelasticity) is required.

For Stream 1, experience with experimental work, including mechanical testing of tissues/materials and wet lab practices, is required; basic biosafety knowledge and exposure to statistics or imaging/DIC analysis are assets.

For Stream 2, familiarity with data analysis, optimization methods, and mathematical modelling is required; experience with constitutive modelling and FEA is an asset.

For Stream 3, background in constitutive modelling and finite element analysis is required; experience with Abaqus/UMAT is an asset.

29. Mechanical testing of humans

Through this project we will be using our new mechanical test system, coupled with wireless ultrasound and electromyography (EMG) to measure the in vivo tissue properties of human soft tissues. We aim to characterize these tissues in live human test subjects. Protocols have been established to measure the mechanics of tissues when they are both relaxed and active. Ultrasound allows us to measure the thickness and structure of the soft tissues we are testing. We will then implement the experimental results in computational and physical models of injury. Models will be constructed both in rigid body dynamic simulations (e.g. Madymo) and in finite element models of isolated body structures. We have recently added a 5th-percentile female crash test dummy to the lab and will conduct experiments with the dummy to validate the simulations. The results of this study will provide valuable new data for the contact properties of live human tissues and insights into injury risk from falls. The ultimate goal of the project is to improve the fidelity of computation and physical models of humans in replicating fall events.

Research area, student roles & skills

Research area: In the Neurospine Lab at SFU we specialize in characterizing the mechanics of biological tissues and materials to better understand and model human injury. We have characterized a range of biological tissues from spinal cords through ribs and work to develop constitutive models to represent the different materials. We recently developed a new mechanical test system that will allow us to test the mechanics of biological tissues in the body. These tissue properties have largely been lacking from the literature, particularly at larger deformations and higher loading rates typical of injury.

Student roles:
The student will work with the graduate students and professor in the lab to conduct human subjects experiments to measure the mechanical properties of the soft tissues. The student will be trained in human ethics, mechanical testing and data analysis during the project. The student will assist in running the custom mechanical test system we have in the lab. In addition the student will learn ultrasound techniques and measure soft tissues with our wireless ultrasound system (Clarius). The student will also assist in measuring muscle activation using an EMG system and characterize the differences in soft tissue structures when the muscles are active and relaxed. The student will then work with the graduate students in the lab to analysis the results of the experiments and write a conference abstract and journal paper presenting the results.

Skills required:
The ideal student for this project is a senior student (> 3rd year) with a background in engineering or medicine with an interest in understanding, preventing or treating human injuries. The student must be able to work well with others and be able to conduct human subjects trials. Experience with mechanical testing systems (e.g. Instron, MTS, etc) is an asset but not required. Experience with finite element or rigid body dynamic modeling is also an asset but not required.

30. Motion capture and Biomechanical Data Analysis

Each year, our research focuses on numerous human movement research studies involving a variety of populations including, persons with autism, cerebral palsy, orthopaedic problems and also typically developing children and adults. Motion capture, force plates, and EMG are used to track and analyze patterns of 3D movement. This research involves expertise in various fields including biomedical, mechanical and electrical engineering, as well as kinesiology. Much data from individuals across the life span (children and adults) has also been previously collected but requires analysis and interpretation using specialized software. Additional data on further participants will be collected over the internship period. These research projects sometimes involve sensor technology validation and testing (wearable sensors, pressure sensors, etc) for use in human movement research. Of importance is the processing and integration of biomechanical data into usable databases through specialized visual 3D software (which will be taught to candidates on arrival). Our lab provides world class facilities, and state-of-the-art hardware and software that will undoubtedly provide students with desirable skills for the future. If you enjoy working with people, biomechanics, 3D software, signal processing and data analysis, this is the place for you! 1) Marcial, N., Kuruganti, U. Chester,V. (2022). The Effect of Age and Walking Speed on Multisegment Foot Kinematics. Proceedings of the North American Congress on Biomechanics. North American Congress on Biomechanics, Ottawa, Canada 2) Pradhan, A., Chester, V., Padhiar, K. (2022). Classification of Autism and Control Gait in Children Using Multisegment Foot Kinematic Features. Bioengineering. 9(10): 1-15. 3) Pradhan, A., Oladi, S., Kuruganti, U., Chester, V. (2020). Classification of Elderly Fallers and Nonfallers Using Force Plate Parameters from Gait and Balance Tasks. Springer Proceedings of the International Symposium on Computer Methods in Biomechanics and Biomedical Engineering,Computer Methods,Imaging and Visualization in Biomechanics and Biomedical Engineering. 36: 339-353.

Research area, student roles & skills

Research area: My specialized area is human movement research - more specifically biomechanics, motion capture, and gait analysis research. We use a 12 camera Vicon motion capture system to track body movement during walking. These infrared cameras track reflective markers located on the skin. Kinematic and kinetic data is computed and used to identify movement deviations. Biomechanical signals are processed using matlab, python, and Visual 3D software. This allows for a greater understanding of atypical and typical motion in the body. In turn, we can increase our understanding of disorders, treatments, and try to improve function and quality of life.

Student roles:
The student will be responsible for operating the motion capture system, collecting data, analyzing data, and using Visual 3D software for data analysis of biomechanical motion capture data. Students play an integral role in patient management and signal quality control during data collections. We have great student research teams here from all over the world - come join us!

Skills required:
Introductory biomechanics knowledge
Introductory Algebra/geometry knowledge (3D data)
Enjoy learning new software and hardware
Previous experience biomechanics data collection is not required, but would be an asset (motion capture will be taught to successful candidates)
Visual 3D experience is not required, but would be an asset (Visual 3D will be taught to successful candidates)
Python/Matlab programming not required, but would be an asset

31. Multichannel Myoelectric Signal Analysis for Neuromuscular Function and Prosthesis Control

The control mechanisms for neuromuscular systems and the ability to produce functions such as movement efficiently have important clinical implications and are of research interest. Restoration of these functions when impaired by injury, loss, disease or aging, require observation and understanding of the control mechanisms. One method to observe neuromuscular function is through the use of surface electrodes to record myoelectric signals (MES) from contracting muscles. The MES measures the result of the neural commands sent to the muscle and provides evidence of various factors including the neural mechanisms responsible for deficiencies and interactions between muscles (agonist, antagonist and synergist). The MES is a useful tool to examine developmental aspects of the neuromuscular system such as adaptations due to age. Recently, advances in MES processing have resulted in new techniques, which are more robust. High-density electromyography (HD-EMG) allows the acquisition of significantly greater numbers of muscle channels and therefore greater information from the muscle as a whole. These new systems allow for the development of topographical (energy) maps, which can then be used to further study muscle activation patterns. This is particularly suited for those with limited muscle physiology due to injury or loss. Recent work from our lab investigating muscle activity (using HD-EMG) of the forearm from a group of healthy adults as well as traumatic and congenital amputees has shown reliable muscle patterns can be detected for various movements using this technology and that the information obtained can be used for better multifunction control of myoelectric prosthetic devices. Further investigation of interlimb coordination with this new technology is warranted including investigation of novel algorithms. This research will also help to develop better prosthesis control systems and advance robotics (e.g. external dermoskeletons).

Research area, student roles & skills

Research area: My background is in the area of human factors and biomedical engineering. My specific research interests include neuromuscular physiology and rehabilitation of clinical populations as well as occupational physiology. The focus of my research is the use of surface electromyography (sEMG) to monitor muscle activity during movement. sEMG is the measurement of the electrical activity at the skin’s surface, that brings about muscle contraction. The sEMG can be used to examine muscle activation patterns for a variety of applications including improved prosthesis design (artificial limbs). Understanding neuromuscular function in movement efficiency will help develop better models of human movement.

Student roles:
The student will be responsible to work with the research team to collect and analyze data using high density EMG from those without physiological and/or neurological conditions as well as clinical participants. In addition, the student will use an isokinetic dynamometer to collect force data from both groups. The student will be responsible to integrate the testing equipment and analyze the resulting data in order to compare the movement patterns between those who have movement limitations and those without. In addition, the student may be required to generate software code to assist with the data analysis. Currently there are many different algorithms that are used to process high density EMG data including pattern classification methods and machine learning algorithms. The student will need to be able to understand these algorithms, develop software utilizing these algorithms and ensure data validity.

Skills required:
The student should have a background in electrical and/or biomedical engineering with a strong interest in human movement. The skills required include familiarization with data acquisition equipment and hardware as well as strong programming skills (Matlab and/or Python). In addition, the student should have strong mathematical skills and the ability to critically analyze published research. The intern must also have a strong background in EMG signal processing and software development including pattern recognition and machine learning algorithms. The student should also have strong communication skills.

32. Multimodal analysis of behavioral data in the context of locomotion

Our lab uses the transcranial magnetic stimulation technique (TMS) to quantify corticospinal excitability and to transiently alter the excitability of the cortex. Responses are recorded via electromyography of various muscles. We also use intertial sensors to quantify locomotion, collect anatomical neuroimaging along with various questionnaires to measure clinical outcomes in patient populations. The project will consist of analyzing the multimodal data set with the goal of comparing locomotor behavior under different conditions.

Research area, student roles & skills

Research area: Our research focuses on the neuronal substrates involved in the control of human locomotion. Areas of expertise include neuroscience, motor control, computer science and engineering. We use techniques such as movement kinematics, EMG, neuronavigated brain stimulation (TMS) and brain imaging with MRI and PET. We study human locomotion both overground and on a split-belt treadmill.

Student roles:
Develop analysis pipelines to facilitate the integration of our multimodal data. Collaborate with graduate students to conduct the project.

Skills required:
Interest in the analysis of biological signals. Interest in teamwork.

33. Nanosensor Enhanced Raman Microscopy for Disease Detection

Enhanced Raman Sensing is an important analytical tool for ultra-sensitive, non-invasive detection. Though Raman sensing has been around for many decades, it is application for cancer detection is new. The Raman fingerprint of cancer cell biomarkers could be used for the early diagnosis of cancers. However, Raman signal is weak in nature, making it hard to be used for clinical applications. Most of the research activity in this field focused on using nano-sized noble metal to enhance detection sensitivity and signal output. However, the toxicity of metallic nanomaterials, the poor reliability of the signal and other drawbacks limit it application for cancer diagnosis. My research group has sucessfuly developed semiconductor based nano sensors to overcome this shortcoming and making nano-semiconductor a competitive candidate for Raman based cancer diagnosis. Our current research focuses on on invigiating novel ways of using liquid biopsies for the detection of diseases, including infectious diseases, cancer, neurodegenerative diseases and others.

Research area, student roles & skills

Research area: I am the principle investigator of Laser Nano Micro Manufacturing Laboratory (LNMM)at TMU. My group develops advanced nano materials for biomedical detection. My group has made significant contribution to the diagnosis of cancer using Surface Enhanced Raman Sensing of human blood samples. Our recent findings were published by Nature Communications, Advanced Science and others.

Student roles:
We are looking for highly motivated undergraduate students to join us to assist us with laboratory research in the abovementioned direction. Student will work with a Ph.D candidate or a postdoctoral fellow. She or he will be trained to operate analytical instrument, such as SEM, TEM , AFM, EDX, and use Mechine Learning tools for statistical anlaysis . Main tasks in the lab will include assisting with experiments and collecting data, preparing plots charts, and conducting literature research. Student will document data and provide a report at the end of the project.

Skills required:
. This a multidisciplinary research area. Student with material engineering, biology and medical science background suits the best for the position. However, student from all engineering disciplines could benefit from this project. Must be familiar with Microsoft office tools. Photoshop editing skill is a plus. Must be cultural sensitivity and able to work in a diverse workforce in multicultural settings.

34. Neuromodulation mechanisms: deep brain electrical stimulation and focused ultrasound

There are several projects in which the student could participate. 1. Human brain oscillations: DBS involves implantation of fine electrodes into the brain, and connecting these to a brain pacemaker. It is used to treat movement disorders (Parkinson disease, dystonia, tremor) and depression. We have years of data collected from intra-operative recordings and perform several experiments intra- and post-operatively on patients undergoing surgery, learning how brain cells respond to specific emotions, motor and cognitive tasks. 2. DBS and plasticity of neural circuits: Our aim is to learn how DBS improves dystonia gradually over months. We believe that DBS alters the excitability of cortical pathways and motor maps. We use EEG and transcranial magnetic stimulation (TMS) to measure excitability and motor maps in DBS ‘off’ and ‘on’ states. Serial EEG and TMS mapping in patients pre- and post-operatively will determine whether excitability and markers of plasticity change over time, as symptoms improve. 3. Imaging and DBS in rodent models: This project is the animal corollary of project 2 aimed to use intrinsic optical imaging to identify the plasticity occurring in animal models with DBS. We have designed instrumentation to allow intrinsic optical imaging in freely moving rodents and will start implanting these devices for longitudinal experiments, using behavior, electrophysiology and immunohistochemistry to measure plasticity. 4. Focused ultrasound neuromodulation in animal models and normal human subjects: Here we are learning the mechanisms of action of low intensity focused ultrasound and test different sonication parameters. We have developed a in vitro instrumentation system to study changes in local field potentials in rat brain slices. In collaboration with engineers and neurologists, we are testing a human transcranial low intensity FUS platform for humans with tremor and anticipate testing it for other conditions and brain targets.

Research area, student roles & skills

Research area: Our lab is dedicated to understanding how therapeutic neuromodulation (deep brain stimulation/DBS and focused ultrasound FUS) affects the brain in humans and animal models. We also focus on developing neural prostheses with the basic science underlying these. This means that we study human physiology using intra-operative microelectrode recordings, post-operative EEG, functional MR imaging and transcranial magnetic stimulation (TMS) in patients with DBS systems. We also study the fundamental mechanisms of DBS and FUS in animal models in vivo and in vitro using electrophysiology, optical imaging, fibre photometry.

Student roles:
The student(s) will participate in data collection and analysis under the direct supervision of a graduate student or post-doctoral fellow. S/he will write a report on their project and present their results at our summer student symposium in August (previous MITACs students have presented at the Alberta Motor Control meeting if they start later and stay until mid-Sep). Students will attend the operating room in order to gain experience with patients undergoing DBS surgery. However the majority of their time is spent in data analysis and experiments in the lab.
1. Human brain oscillations: For this project, the summer student will participate in data collection in the operating room with the rest of the team. Most of their time will
be spent digitizing the data we collect, pre-processing it, and analysing the local field potentials and cellular firing patterns. Depending on the student’s background they may write code to do this, or may use previously written Matlab or Python code.
2. DBS and plasticity of neural circuits: The student will help the postdoctoral fellow with data collection and analysis of TMS measures in patients with DBS systems. This will
include using Matlab scripts and may involve writing code or further programming.
3. Imaging and DBS in rodent models: Again depending on the student’s background, they may participate in characterizing the instrumentation, implanting it into the rodents, or analyzing the imaging, electrophysiological or behavioural data generated.
4. Focused ultrasound neuromodulation: The student will work others in the lab performing experiments in rat brain slices measuring local field potential, applying FUS to the
slices. The student may also participate in ongoing human experiments of low intensity neuromodulatory FUS.

Skills required:
Senior undergraduate level engineering / physics or physiology are ideal. Those with a neuroscience background or experience in electrical biomedical engineering are preferred.

35. Next-Generation Ultrasound Technologies for Medical Imaging

This internship invites a motivated student to contribute to the development of next-generation ultrasound technologies for medical imaging and image-guided interventions. Depending on the student’s background and interests, the project may involve several steps of the innovation chain: mechanical and acoustic probe design, material selection, prototyping, acquisition electronics, simulation, signal processing, image formation and experimental validation. The general goal is to make ultrasound systems more precise, accessible and better adapted to emerging biomedical applications. Possible themes include high-resolution imaging, compact or specialized probes, focused ultrasound, transcranial applications, neuromodulation, treatment monitoring and the analysis of experimental signals. The internship topic will be defined with the selected student so that it matches their strengths while allowing them to discover new tools. The intern will join an interdisciplinary research environment where modelling, experiments and technological development are combined. They may work with graduate students, take part in laboratory tests, analyze real data and contribute to a solution with potential impact in healthcare. This project is especially suited for someone who enjoys learning, building, measuring, programming and connecting theory to medical applications.

Research area, student roles & skills

Research area: My research focuses on ultrasound technologies for medical imaging and therapeutic applications. We develop tools that connect acoustics, mechanics, materials, electronics and signal processing to design new probes, improve image formation and guide non-invasive interventions. Applications include high-resolution imaging, focused ultrasound, transcranial approaches and the experimental characterization of ultrasound systems.

Student roles:
The intern will play an active role in the development and validation of ultrasound technologies for medical imaging and therapeutic applications. Depending on their background, they may contribute to the design of an experimental setup, the fabrication or integration of probe components, ultrasound data acquisition, signal processing, image formation or the analysis of experimental results.

They will be encouraged to take part in all stages of the project: targeted literature review, definition of technical objectives, selection of methods, experiments, critical data analysis and presentation of results to the team. The internship will provide an opportunity to connect concepts from engineering, physics and biomedical sciences to concrete healthcare applications.

The selected student will work in collaboration with graduate students and laboratory members, while progressively developing independence. They will be expected to document their work carefully, share progress during team meetings and contribute to the advancement of an interdisciplinary research project. The role can be adapted to highlight the student’s strengths and support the development of new skills.

Skills required:
Desired background: student in engineering, physics, applied sciences, computer science or a related field, with strong curiosity for biomedical technologies. Experience in scientific programming, signal processing, electronics, mechanical design, acoustics, materials, simulation or experimental work is an asset. The student does not need to master all these areas: we are mainly looking for someone rigorous, independent, creative, able to work in a team and motivated to learn in an interdisciplinary environment.

36. Oncoprofiler cancer diagnosis

The cancer diagnosis process may seem long and frustrating because of the high false-positive rate; 10% for a mammogram and 30-50% for low-dose CT, the gold standard methods for screening breast cancer and lung cancer, respectively. Follow-up tests have to be performed with additional imaging or tissue-biopsy to confirm the diagnosis. In addition to the invasive nature of these processes, image and tissue biopsy-based diagnosis methods can detect tumors only when it is above 1 cm size: by then some cancers progress to advanced stages. As a non-invasive test, blood-based liquid biopsy diagnostics has the potential to overcome the drawbacks of current techniques. Proteins and peptides in blood plasma are commonly used as biomarkers to indicate the presence of cancer. Since these biomarkers are not unique to cancer, they are not used to confirm the diagnosis but to indicate further cancer tests. Besides, blood biomarkers cannot predict the localization of cancer or sub-typing of cancer without histology. Detection of mutations in the very early stages is almost impossible. Therefore, existing methods of liquid biopsy remain as a complementary tool in cancer diagnosis. The clinical utility of blood-based cancer diagnosis is still minimal. Researchers at Toronto Metropolitan University have invented OncoProfiler, a quantum sensor enhanced Raman microscopy. The device offers single-molecular detection sensitivity and is capable of identifying biomarkers that are previous undetectable due to their extreme low concentration in blood stream. By employing new biomarkers, OncoProfiler has demonstrated high accuracy in cancer diagnosis from patient blood samples. The proposed project tests the performance of OncoProfiler with a large set of blood samples from patients with confirmed cancer diagnosis. We aim to test 12 different types of cancers, including colorectal, bladder, head and neck, hepatobiliary, lung, lymphoma, leukemia, ovary, pancreas, myeloma, esophageal/gastric, breast, thyroid, kidney, endometrium, prostate, melanoma, and sarcoma.

Research area, student roles & skills

Research area: Dr. Tan is an Affiliate Scientists at Li Ka Shing Knowledge Institute, a part of Unity Health Toronto. She has been working in the field of ultrafast laser Nano material synthesis and application for about two decades. To her credit, she published over 150 high impact factor journal publications and several patents. Dr. Tan’s research group has made significant contribution to the research in designing nanomaterial for multiple bio-based applications. Her most recent research focuses on nano sensors detection of blood-based biomarkers for disease diagnosis.

Student roles:
Student will work with a Ph.D candidate or a postdoctoral fellow. She or he will be trained to operate analytical instrument, such as Raman Microscopy and use machine learning tools for statistical analysis. Main tasks in the lab will include assisting with experiments and collecting data, preparing plots and charts, generate scientific illustrations for manuscripts and conducting literature research.

Skills required:
This is a multidisciplinary research area. Students with a biology background suits the best for the position. However, students from all engineering disciplines could benefit from this project. Must be familiar with Microsoft office tools. Photoshop editing skill is a plus. Must be culturally sensitive and able to work in a diverse workforce in multicultural settings.

37. Quantifying Trust in Wearable Devices for Cognitive Workload Assessment

The objective of the project is to develop a conceptual and analytical framework to quantify human trust in wearable devices that assess cognitive workload. Students will review existing trust measures, adapt them to the specific context of workload-assessing wearables, and create synthetic scenarios and datasets to explore how trust might vary with device behavior and feedback design. The activities include: - Literature search on existing trust assessment and measures, and how the human's cognitive load affects theit trustung in the device feedback - Based on the literature, define trust-related variables tailored to workload-assessing wearables, - Create simple generative rules to synthesize datasets that capture relationships between acuracy, relaibility, different user profiles (e.g., cautious vs. automation‑prone users). - Create synthetic datasets and scenarios to explore relationships between trust, reliance, and workload indicators. - Analyze the synthetic datasets using basic statistical methods to compare trust indicators across conditions (e.g., accurate vs. inaccurate wearable, transparent vs. non-transparent feedback), examine relationships between trust and modeled workload (e.g., does high workload lead to more or less reliance on the wearable?), explore simple regression models that predict reliance on the wearable from trust, perceived accuracy, and scenario variables.

Research area, student roles & skills

Research area: Biomedical engineering, biometrics, biometric signal processing, machine learning, probabilistic causal models, wearable devices, decision support

Student roles:
The student will work both individually and in a team of other 4-6 research students 4-5 days a week in a university research lab on campus.
The student will be provided with a desktop computer and computer desk.
The student will work with a lab software to perform synthesis and analysis on the data, already collected in the lab or simulated/generated.
The student will meet with the supervisor 3-4 times a week, participate in lab seminars, present at some seminar, and write reports (2-3 times per term).

Skills required:
Basic biomedical or electrical engineering knowledge, signal processing, basic statictics, Python and related software

38. Quantitative assessment of unstable sitting control using a smart balance board

Balance problems are very common post-stroke. In the early stages of stroke recovery, people are often unable to stand, which limits a therapist’s ability to assess the effects of stroke on balance control and predict future capacity for independent mobility. Motivated by its prognostic relevance, also upper body control during sitting has been used to assess balance impairments post-stroke. While the ability to sit can be assessed very early in the rehabilitation phase, maximal sitting balance scores are oftentimes observed, resulting in a major ceiling effect. One possibility to avoid floor or ceiling effects is to assess a modified sitting posture using a novel sitting paradigm that is safe, but more challenging than conventional sitting. For this purpose, we developed and validated an instrumented (smart) wobble board capturing its tilt angles during unstable sitting. Our objective is to implement the smart wobble board in a clinical setting and validate the obtained kinematic data. I) The trainee's first task will be to embed the smart wobble board into an existing test environment. More specifically, the trainee will need to synchronize the smart wobble board with other experimental equipment and develop a software interface, allowing the user to store and visualize the acquired tilt angles on a tabloid. II) The trainee’s second task will be to validate the kinematic data. First, tilt angles during unstable sitting will be cross-checked against those obtained via a conventional motion capture system. Second, mechanistic measures of postural steadiness, obtained from the tilt angles, will be compared between non-disabled young individuals and non-disabled elderly individuals. Third, the reliability of the obtained measures will be explored by having half of the non-disabled study participants return for a second assessment session. The trainee will execute the experiments, assess kinematic validity, and identify differences between the age groups.

Research area, student roles & skills

Research area: Dr. Albert Vette is currently a tenured Full Professor in the Department of Mechanical Engineering, University of Alberta, and a Research Scientist at the Glenrose Rehabilitation Hospital, Edmonton, Canada. His work is centered at the interface between musculoskeletal biomechanics, neuromuscular control, and rehabilitation engineering. Particular research interests of Dr. Vette include the dynamics and control of neuromuscular processes; the modeling of physiological systems; sensory-motor integration during human movement and posture; and assistive technology for individuals with neurological disorders.

Student roles:
The trainee's first task will be to synchronize the smart wobble board with other experimental equipment and develop a software interface allowing the user to store and visualize the acquired tilt angles on a tabloid. The second task will be to complete the validation experiments and assess the degree of correlation between the wobble board and motion capture measurements. Finally, she/he will perform the experiments in the two sample populations, compute the mechanistic quantitative measures, and identify age differences. By performing this work, the trainee will gain valuable practical experience on a clinical research question. In particular, she/he will be able to apply her academic knowledge to a clinical problem, but also learn to overcome technical and experimental hurdles not present in the academic environment. She/he will work in a highly interdisciplinary environment at our laboratory. She/he will benefit from a wide range of expertise, learn about clinical challenges and needs, and develop a professional network that will be beneficial in the future. We plan to publish the work in a clinically relevant journal, which will allow the trainee to gain valuable writing experience and further strengthen her resume.

Skills required:
The student should have a background in Mechanical, Computer, Electrical, or Biomedical Engineering - or any related field. Students should have some knowledge in data acquisition, processing and analysis, and be generally interested in the biomechanics research field.

39. Ring Transducer Design for Microscopy-Based Ultrasound Bioeffects Studies

This project involves the design and optimization of a ring-shaped ultrasound transducer intended for integration into optical microscopy setups used in ultrasound bioeffects research. The student will use COMSOL Multiphysics to simulate and evaluate different ring transducer geometries, with particular attention to acoustic performance, spatial constraints, and optical access required for microscopy. Simulation results will be analyzed to guide design choices and ensure that the transducer meets the requirements of experimental and biological studies. In addition, the project includes investigating appropriate fabrication techniques and designing a functional casing that supports precise alignment, ease of integration, and experimental robustness. The main goal is to develop a transducer design that enables controlled ultrasound exposure while maintaining compatibility with high-resolution optical imaging. Through this work, the student will develop skills in finite element modelling, data analysis, and engineering design optimization, while gaining hands-on experience with interdisciplinary challenges at the interface of acoustics, biomedical engineering, and experimental instrumentation.

Research area, student roles & skills

Research area: This research area focuses on the design and optimization of ultrasound transducers for use in ultrasound bioeffects research coupled with optical microscopy. It combines acoustics, finite-element modelling, and experimental instrumentation to enable precise, controlled ultrasound exposure while preserving high‑resolution optical access. Using computational tools such as COMSOL Multiphysics, the work explores how transducer geometry, acoustic performance, and physical constraints interact in integrated imaging systems. The research also addresses practical considerations in fabrication and mechanical design, supporting robust experimental implementation at the intersection of biomedical engineering, ultrasound physics, and microscopy-based biological research.

Student roles:
The student will take a central role in the computational design and engineering optimization of a ring‑shaped ultrasound transducer for microscopy‑based bioeffects research. Drawing on a background in acoustics, biomedical engineering, physics, or related disciplines, the student will develop and iterate finite element models to evaluate acoustic performance under strict spatial and optical constraints. They will analyze simulation outputs using appropriate data analysis tools to inform design decisions and refine transducer geometries. The student will also investigate feasible fabrication approaches and contribute to the design of a functional casing that supports alignment, integration, and experimental robustness. Throughout the project, the student will clearly document methods and results while applying problem‑solving and iterative design skills in an interdisciplinary research environment.

Skills required:
Suggested student background:
• Background in acoustics, biomedical engineering, physics, mechanical or mechatronics engineering
• Preferred experience with numerical simulation or finite element modelling (COMSOL preferred, but not required)
• Basic data analysis and interpretation skills (e.g., MATLAB, Python, or similar tools)
• Understanding of experimental constraints and design requirements
• Interest in biomedical imaging, ultrasound, or biophysical effects
• Strong problem-solving skills and willingness to iterate on designs
• Ability to document technical work clearly

40. Robot Learning for Surgical Skill Acquisition: Task Abstraction, Demonstration Data Collection, and Algorithm Testing

Robot learning has enabled significant advances in manipulation through imitation learning and large-scale demonstration datasets. However, surgical robotics lacks structured task definitions and datasets that capture consistent expert demonstrations suitable for training learning-based skills. This four-month internship covers a complete, scaled-down robot learning pipeline: abstracting representative surgical subtasks, collecting demonstrations, and testing learning algorithms on the resulting data, under faculty and graduate-student supervision. The intern will first help identify and formalize two to three subtasks that are repeatedly performed during surgical procedures, such as precision targeting, curved path following, or soft tissue manipulation, defining clear start and end conditions, success criteria, and difficulty variations for each. For each abstracted task, the intern will support controlled demonstration trials on phantom tissue models and simulators emulating microsurgical conditions, recording multimodal data including end-effector trajectories, joint positions, tool orientation, control inputs, and, where available, force/torque and visual observations synchronized with robot state, across a sufficient number of repetitions per task. Using the curated dataset, the intern will test and adapt existing implementations of state-of-the-art imitation-learning algorithms and baselines, training them on each abstracted task and comparing learned performance using simple, well-defined metrics. The expected outcomes are a small set of clearly defined surgical subtasks; a labeled multimodal demonstration dataset for each; and a working evaluation of one or more imitation-learning algorithms, summarized in a short technical report. This work contributes a reusable pipeline and dataset for future research in learning-based surgical skill acquisition.

Research area, student roles & skills

Research area: The project is intended as research towards autonomous robotic surgery. Robot learning enables systems to acquire manipulation skills directly from expert demonstrations rather than hand-coded rules. In surgical robotics, such demonstrations can be obtained from robotic systems interacting with phantom tissue models and simulated environments approximating microsurgical conditions. The internship focuses on abstracting a small set of representative, repeatedly performed surgical subtasks, collecting demonstration datasets for them, and testing and adapting state-of-the-art imitation-learning algorithms, such as Action Chunking Transformer and related policies, to learn these surgical skills from data.

Student roles:
Over the four-month internship, the student will work through a complete robot learning pipeline for surgical skill acquisition, from task definition to dataset collection to algorithm testing, under the close guidance of faculty and graduate researchers.

In the first month, the intern will be onboarded to the experimental setup, existing codebase, and data formats, and will work with the supervisory team to identify and abstract two to three surgical subtasks that are repeatedly performed in practice, such as precision targeting, curved path following, or soft tissue manipulation. For each task, the intern will help define clear start and end conditions, success criteria, and a simple protocol for repeatable demonstration trials.

In the second month, the intern will support supervised data collection sessions on phantom tissue models and in simulation for each abstracted task, and will implement scripts to record, clean, and synchronize multimodal data streams, including robot kinematics, tool state, and, where available, force/torque and camera observations, organizing them into a standardized, labeled dataset.

In the third month, the intern will set up and run existing implementations of state-of-the-art imitation-learning algorithms, such as Action Chunking Transformer and comparable behavior-cloning baselines, training them on the collected dataset for each task and beginning basic performance evaluation.

In the final month, the intern will refine and compare algorithm performance across tasks, contribute to simple visualization tools for replaying trajectories and learned behavior, and document the pipeline, dataset, and results in a final report and presentation. This internship offers hands-on, supervised experience spanning surgical robotics, dataset engineering, and applied robot learning.

Skills required:
The ideal candidate is an undergraduate student in mechanical engineering, electrical engineering, computer engineering, biomedical engineering, computer science, or a related field. Working knowledge of Python is required, and familiarity with PyTorch or another deep learning framework is a strong asset. Coursework or project experience in robotics, machine learning, or data analysis is beneficial. Prior exposure to ROS, sensor data, or computer vision is helpful but not required. The student should be organized, detail-oriented, and comfortable running and adapting existing code under supervision. Curiosity about robot learning, surgical robotics, and imitation learning is highly desirable.

41. Secure API and Software Interface for Wearable Data

The objective of the project is to design and implement a secure communication channel, backend API, and user interface to receive, store, and visualize wearable data streamed from a device or simulator to a laptop. Expected project activities: - Define a data format and schema for wearable time‑series (e.g., JSON or binary messages with timestamps and sensor fields). - Implement a secure communication mechanism (e.g., encrypted link over BLE/Wi‑Fi, or simulation thereof) that ensures confidentiality and integrity of transmitted data. - Develop a backend service (REST or WebSocket) to ingest, validate, store, and serve the data. - Design and implement a desktop or web‑based interface that displays live heart rate and recent trends, and provides controls such as start/stop recording and data export. - Document the API (endpoints, payloads, authentication) and provide usage examples. - Evaluate usability and security trade‑offs, and reflect on potential threats and mitigations.

Research area, student roles & skills

Research area: Biometrics, biometric signal processing, biomedical engineering, probabilisitc causal models, machine learning and machine reasoning, decision support, wearable devices

Student roles:
The student will work both individually and in a team of other 4-6 research students 4-5 days a week in a university research lab on campus.
The student will be provided with a desktop computer and computer desk.
The student will meet with the supervisor 3-4 times a week, participate in lab seminars, present at some seminar, and write reports (2-3 times per term).

Skills required:
Experience with a high‑level programming language (Python, JavaScript, or similar); Introductory course in networking or web development is an asset.
Basic understanding of cryptographic concepts (encryption, authentication) is helpful but not mandatory.

42. Smart garment for people living with Parkinson's disease

Parkinson's disease (PD) is a chronic disorder that results in uncontrollable bodily movements that greatly impact an individual's autonomy. Driven by population aging and the consequences of industrialization, it has the fastest growth among neurological disorders; worldwide, the number of persons living with PD is projected to exceed 12 million by 2040. In Alberta, over 10,000 people live with PD while there is only one PD specialist for every 735 people affected. Yet, patients with neurological disorders such as PD require consistent monitoring and treatment. In addition, there is still no cure for PD and most diagnoses are based on clinical testing such as the Movement Disorder Society-sponsored Revision of Unified Parkinson's Disease Rating Scale. Early signs of the disease are difficult to determine, and a lack of objective measures reduces the chance of a satisfactory quality of life. Thus, there is a critical need for solutions for the diagnosis, condition monitoring, and treatment of PD. Any improvement will have a major impact on the Alberta population: patients with PD, medical staff and caregivers, family, and friends. The project aims to develop a comfortable smart garment for neurological function monitoring and enhancement to help in everyday function for users living with PD. The garment will integrate sensors to monitor the patient's evolving condition and actuators to combat tremors. The embedded biosensors will also allow detecting changes in individuals with genetic linkages to the disorder for an early diagnosis. The technologies developed will also benefit other neurological diseases such as multiple sclerosis, epilepsy, and pediatric seizures.

Research area, student roles & skills

Research area: Smart textiles can sense changing conditions, perform actions, and adapt their performance to the environment. When integrated into garments, they allow harnessing the large contact surface area with the skin to provide a multitude of sensing and actuating functions to the garment. Current applications including monitoring vital signs and providing heat and cooling to the body. Smart garments’ potential impact in the medical field is immense. They will be a life changer for people benefitting from it.

Student roles:
The mission of the student in this project includes the following tasks:
• Prepare an experimental design
• Produce samples
• Characterize the sample performance
• Analyze the results
• Produce technical reports
• Prepare progress presentations

The intern will be trained on different manufacturing and characterization techniques relevant to sensors and actuators, and their integration into a garment in the state-of-the-art laboratories at the University of Alberta. The student will work in close collaboration with the Master, PhD, and other undergraduate students in the team. Throughout the internship, they will also interact with the different researchers in the team, whose expertise cover the different aspects of the question: neuroscience, textile science, materials engineering, biosensors, electrical stimulation, machine learning, evidence-supported decision, and technology validation.

Skills required:
In addition to solid skills in electrical, materials, and/or textile engineering, it is critical that the student is curious and rigorous, as well as open to interdisciplinary research. They should be able to work independently while displaying a good ability for teamwork. Oral and written communication skills are important as well. Some lab work experience, for instance at preparing samples and characterizing their performance, as well as prior experience in being part of studies with human participants are an asset.

43. Synthetic Physiological Signal Generation and Data Augmentation

The objective of the project is to develop a tool to generate synthetic physiological signals (e.g., heart rate, activity traces, possibly simplified photoplethysmography - PPG) to augment limited wearable datasets and study the impact of synthetic data on downstream models. The project activities include: - Analyze an existing physiological dataset to understand typical value ranges, patterns (rest, activity, recovery), and noise characteristics. - Design rule‑based or generative models that produce realistic heart‑rate and activity time‑series under different scenarios (e.g., sedentary day, exercise session). - Incorporate realistic artifacts such as noise, motion spikes, and missing segments into the synthetic data. - Compare statistical properties (distributions, autocorrelation, transition patterns) of real vs. synthetic signals. - Train simple ML models (e.g., regressors or classifiers) with and without synthetic augmentation and compare performance on some existing open real data. - Document the generator design, evaluation results, and limitations.

Research area, student roles & skills

Research area: Biomedical engineering, biometrics, biometric signal processing, machine learning, probabilistic causal models, wearable devices, decision support

Student roles:
The student will work both individually and in a team of other 4-6 research students 4-5 days a week in a university research lab on campus.
The student will be provided with a desktop computer and computer desk.
The student will work with a lab software to perform synthesis and analysis on the data, already collected in the lab and simulated/generated.
The student will meet with the supervisor 3-4 times a week, participate in lab seminars, present at some seminar, and write reports (2-3 times per term).

Skills required:
Basic biomedical or electrical engineering knowledge, signal processing, basic statictics, Python and related software

44. Using artificial intelligence (AI) to study the neuroscience of skilled movement

The goal of this project is to design and build an automated system (hardware and software) for training and analyzing mice behavior during a reach-to-grasp task. This task challenges animals to reach for a food reward with one hand through a thin vertical window and has been used for decades to evaluate motor control and learning in both health and disease (stroke, Parkinson’s, spinal cord injury). By automating this task, we aim to reduce the time and variability associated with manual training of the animals and frame-by-frame video scoring by experimenters. The goal is to equip the system with an automated food delivery module, a computer vision strategy to automatically classify trial outcome (success and failure) and a machine-learning approach to automatically quantify different movement features (speed, accuracy, etc.).

Research area, student roles & skills

Research area: Our lab’s main interest is to decipher the anatomical and functional logic of neural circuits linking sensory and motor regions of the brain to reveal how they help orchestrate the production and learning of skilled movements in mice. By gaining a better understanding of these fundamental mechanisms, our ultimate goal is to develop new therapeutic treatments for neurodevelopmental disorders and acquired brain injuries linked to sensorimotor deficits such as cerebral palsy, autism, traumatic brain injury and stroke.

Student roles:
Depending on the student's background and interests, the role of the student may encompass:
- Building an automated food delivery system (designing hardware for 3D printing, developing microcontroller firmware to manage peripheral electronics, synchronizing video recordings with trial start)
- Programming AI algorithms to classify trial outcome
- Programming machine learning data analysis pipelines for movement analysis using DeepLabCut
- Creating unified data storage framework
- Programming user interfaces
- Training mice on motor task
- Creating scientific figures
- Researching the literature

Skills required:
We are looking for highly motivated students from the fields of biomedical, electrical, mechanical or computer engineering or from the fields of neurosciences, biomedical sciences or rehabilitation with coding skills (Python or Matlab), knowledge of machine-learning and/or robotics skills. Students should have good communication skills and the ability to work effectively within a team.
Candidates with diverse skills and career objectives will be considered.

45. Validation of an ankle torque sensor to quantify force generation dynamics

Recent developments in the field of neurorehabilitation suggest that functional electrical stimulation (FES) may have the potential to facilitate standing and walking in people with spinal cord injury. However, the time delay from muscle stimulation to torque generation (= torque generation delay) might threaten postural stability and needs to be accounted for by envisioned closed-loop FES control strategies. In order to determine the torque generation delay for one of the most critical joints during stance control, the first objective of this project is to develop a load cell-based sensor device that can measure isometric ankle torques at different joint angles. The second objective is to use the sensor in healthy individuals to quantify the torque generation delay as a function of muscle activation frequency and amplitude. The obtained results will enhance our knowledge on torque generation delays and assist in developing better control strategies for neuroprostheses.

Research area, student roles & skills

Research area: Dr. Albert Vette is currently a tenured Full Professor in the Department of Mechanical Engineering, University of Alberta, and a Research Scientist at the Glenrose Rehabilitation Hospital, Edmonton, Canada. His work is centered at the interface between musculoskeletal biomechanics, neuromuscular control, and rehabilitation engineering. Particular research interests of Dr. Vette include the dynamics and control of neuromuscular processes; the modeling of physiological systems; sensory-motor integration during human movement and posture; and assistive technology for individuals with neurological disorders.

Student roles:
The first component of this project, i.e., the development of the torque sensor device, is currently underway. Our expectation is to have a final design of the sensor device by the end of summer 2026 and prototyped by the end of fall 2026. In light of this, the Globalink 2027 student will work on the second component of the project. Specific tasks are:

(1) To integrate the torque sensor device in an experimental setting (that includes electromyography measurements) to validate the torque readings and ensure smooth and accurate data transmission/acquisition.
(2) To perform experiments in healthy individuals to acquire the necessary biomechanical and electrophysiological data for quantifying the torque generation delay.
(3) To process and analyse the acquired data to characterize the relationship between muscle activation (amplitude and frequency) and torque generation. Data will be analyzed in terms of time delay magnitude and muscle-fatigue resistance.

Note that all work will be performed under continuous supervision and guidance from Dr. Vette and his graduate students.

Skills required:
Preferably, applicants should have a background in Mechanical, Computer, Electrical, or Biomedical Engineering (or related field). Students should have some knowledge in device development, data acquisition, processing and analysis, and be generally interested in the biomechanics research field.

46. Wearable Breathing-Rate Monitoring and Analysis

The objective of the project is to investigate wearable solutions to measure breathing rate and related respiratory metrics using one or more sensing modalities, and evaluate their accuracy and robustness under everyday conditions. Expected tasks: - Review different wearable approaches to respiratory monitoring (e.g., chest straps with stretch sensors, accelerometers, wrist PPG‑derived respiration). - Select and implement at least one or two sensor configurations (e.g., chest‑mounted stretch/IMU and/or wrist PPG) and develop firmware or scripts to collect synchronized data. - Design signal processing algorithms for respiratory rate estimation (e.g., band‑pass filtering, peak detection, spectral methods) for each modality. - Establish a reference method (manual breath counts or a reference device, if available) and collect data across conditions (rest, talking, light activity). - Quantify estimation errors and robustness to motion and artifacts, compare modalities, and analyze relationships between breathing rate, heart rate, and activity.

Research area, student roles & skills

Research area: Biomedical engineering, biometrics, biometric signal processing, machine learning, probabilistic causal models, wearable devices, decision support

Student roles:
The student will work both individually and in a team of other 4-6 research students 4-5 days a week in a university research lab on campus.
The student will be provided with a selection of research-grade low-power wearable sensor components, desktop computer and computer desk.
The student will work with a lab software to perform signal processing and analysis on the data, already collected in the lab or simulated using signal generators.
The student will meet with the supervisor 3-4 times a week, participate in lab seminars, present at some seminar, and write reports (2-3 times per term).

Skills required:
Basic biomedical or electrical engineering knowledge, signal processing, basic statictics, Python and related software

47. Wearable Electrochemical Platform for Continuous Hormone Monitoring

Continuous hormone monitoring holds transformative potential for personalized health management, fertility tracking, stress assessment, and chronic disease management. Traditional hormone analysis relies on centralized laboratory testing using immunoassays or mass spectrometry, which are time-consuming, costly, and require trained personnel. This project aims to develop a non-invasive or minimally invasive wearable electrochemical biosensor platform capable of real-time, continuous monitoring of key hormones, including cortisol, estradiol, and progesterone, directly from biofluids such as sweat, interstitial fluid, or saliva. The platform will integrate microfluidic sample handling, affinity-based biorecognition elements (aptamers or antibodies), and signal transduction layers into a flexible, skin-conformal device compatible with wireless readout electronics. This research sits at the intersection of materials science, electrochemistry, and biomedical engineering.

Research area, student roles & skills

Research area: Our research group specializes in flexible, wearable electrochemical biosensors for continuous, non-invasive hormone monitoring in biofluids such as sweat, interstitial fluid, and saliva. We work at the intersection of materials science, microfluidics, and bioanalytical chemistry, integrating affinity-based biorecognition elements with advanced electrode architectures to achieve clinically relevant sensitivity in complex matrices. Detection strategies, including differential pulse voltammetry and electrochemical impedance spectroscopy, are translated into miniaturized, wireless-compatible formats for real-time, longitudinal monitoring outside laboratory settings. Current projects target hormones involved in stress response, reproductive health, and metabolic regulation, advancing personalized point-of-care health management through wearable sensing technologies.

Student roles:
• Design and fabricate flexible electrochemical sensor arrays functionalized with hormone-specific aptamers or antibody conjugates.
• Optimize surface chemistry and electrode modification strategies to achieve clinically relevant detection limits (pg/mL to ng/mL range).

Skills required:
• Background in Chemistry, Biochemistry, Biomedical Engineering, or related field
• Experience with laboratory wet chemistry and surface functionalization
• Knowledge of immunoassay methods (ELISA)

48. Wearable Musle-Activity and Gastro-Activity Sensing

Design and prototype a wearable system that measures muscle activity (EMG) and gastrointestinal activity (e.g., using abdominal surface electrodes) to explore early markers of seizures. The project includes the following parts: - Selecting appropriate EMG and bio‑sensors, designing electrode placement, and implementing low‑noise analog front‑end and microcontroller firmware for continuous sampling and timestamping. - Implementing signal filtering, artifact removal, feature extraction (e.g., muscle activation patterns, slow‑wave GI activity), and experimenting with temporal ML methods (e.g., regression, simple dynamic Bayesian networks, or sequence classifiers) to detect pre‑ictal patterns from recorded episodes. - Performing data analysis and imputation: handling missing segments (due to motion or poor contact) via imputation methods and evaluating how imputation affects seizure‑prediction performance, including basic statistical analysis of false alarms vs. detection rate. Expected outcomes include hardware prototype or a realistic sensor simulator, firmware and analysis code, and a report that documents signal characteristics, feature design, and preliminary seizure‑prediction performance on pilot data or simulated crisis events.

Research area, student roles & skills

Research area: Biomedical engineering, biometrics, biometric signal processing, machine learning, probabilistic causal models, wearable devices, decision support,

Student roles:
The student will work in a team of other 4-6 research students 4-5 days a week in a university research lab on campus.
The student will be provided with a selection of research-grade low-power wearable sensor components, desktop computer and computer desk.
The student will work with a lab software to perform signal processing and analysis on the data, already collected in the lab or simulated using signal generators.
The student will meet with the supervisor 3-4 times a week, participate in lab seminars, present at some seminar, and write reports (2-3 times per term).

Skills required:
Basic biomedical or electrical engineering knowledge, embedded design knowledge, signal processing, basic statictics, Python and related software